Evidence map›Paper›PMID 28450031›Full record

ArticleChest2017

Racial and Ethnic Disparities in Early-Stage Lung Cancer Survival.

Samir Soneji, Nichole T Tanner, Gerard A Silvestri, Christopher S Lathan, William Black

Open access · greenAbstract read
In one paragraph

Article in Chest, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed, 5 pooled it
4.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 5 syntheses or guidelines pooled it, 131 citations in OpenAlex.

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16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Samir SonejiDartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH; Geisel School of Medicine at Dartmouth, Lebanon, NH; Norris Cotton Cancer Center, Lebanon, NH. Electronic address: samir.soneji@dartmouth.edu.
Nichole T TannerMedical University of South Carolina Thoracic Oncology Research Group and Division of Pulmonary Critical Care Medicine; Ralph H. Johnson Veterans Affairs Hospital and Health Equity and Rural Outreach Innovation Center, Charleston, SC.
Gerard A SilvestriMedical University of South Carolina Thoracic Oncology Research Group and Division of Pulmonary Critical Care Medicine.
Christopher S LathanDivision of Population Sciences, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
William BlackDartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH; Department of Radiology, Geisel School of Medicine at Dartmouth, Lebanon, NH; Department of Community and Family Medicine, Geisel School of Medicine at Dartmouth, Lebanon, NH; Geisel School of Medicine at Dartmouth, Lebanon, NH; Norris Cotton Cancer Center, Lebanon, NH.
Cotton (United States) · USDana-Farber Cancer Institute · USDartmouth Institute for Health Policy and Clinical Practice · USMedical University of South Carolina · USRalph H. Johnson VA Medical Center · US

Funding

Translational Science Laboratory Shared ResourceP30CA138313 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI RAYMOND N. DUBOIS · 2009 to 2026
$42.7M
Challenges to effective implementation of lung cancer screeningR21CA197912 · NCI · DARTMOUTH COLLEGE · PI SONEJI, SAMIR SURESH · 2015 to 2017
$388k
NCI NIH HHS P30 CA138313NCI NIH HHS R21 CA197912
6 · The paper itself

Abstract

backgroundBlack patients with lung cancer diagnosed at early stages-for which surgical resection offers a potential cure-experience worse overall survival than do their white counterparts. We undertook a population-based study to estimate the racial and ethnic disparity in death from competing causes and assessed its contribution to the gap in overall survival among patients with early-stage lung cancer.

methodsWe collected survival time data for 105,121 Hispanic, non-Hispanic Asian, non-Hispanic black, and non-Hispanic white patients with early-stage (IA, IB, IIA, and IIB) lung cancer diagnosed between 2004 and 2013 from the Surveillance, Epidemiology, and End-Results registries. We modeled survival time using competing risk regression and included as covariates sex, age at diagnosis, race/ethnicity, stage at diagnosis, histologic type, type of surgical resection, and radiation sequence.

resultsAdjusting for demographic, clinical, and treatment characteristics, non-Hispanic blacks experienced worse overall survival compared with non-Hispanic whites (adjusted hazard ratio [aHR], 1.05; 95% CI, 1.02-1.08), whereas Hispanics and non-Hispanic Asians experienced better overall survival (aHR, 0.93; 95% CI, 0.89-0.98; and aHR, 0.82; 95% CI, 0.79-0.86, respectively). Worse survival from competing causes of death, such as cardiovascular disease and other cancers-rather than from lung cancer itself-led to the disparity in overall survival among non-Hispanic blacks (adjusted relative risk, 1.07; 95% CI, 1.02-1.12).

conclusionsNarrowing racial and ethnic disparities in survival among patients with early-stage lung cancer will rely on more than just equalizing access to surgical resection and will need to include better management and treatment of smoking-related comorbidities and diseases.

Indexed as

Health Status DisparitiesAdultAgedAged, 80 and overEthnicityFemaleHumansLung NeoplasmsMaleMiddle AgedNeoplasm StagingSEER ProgramSurvival RateUnited StatesWhite Peopledisparitieslung cancersurgical oncology

Identifiers

PMID28450031
PMCPMC5812758
OpenAlexW2609906953

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.