ArticleSleep medicine2017
Allostatic load in early pregnancy is associated with poor sleep quality.
Article in Sleep medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Allostatic Load Measurement: A Systematic Review of Reviews, Database Inventory, and Considerations for Neighborhood Research.International journal of environmental research and public health · 2022Pooled it
- Experiences of Racism and Risk of Preeclampsia in the Black Women's Health Study.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Maternal sleep deprivation and developmental programming of brain aging trajectories in offspring.Biogerontology · 2026Review
- Disparities in Allostatic Load Among Different Races: A Comprehensive Scoping Review.Journal of racial and ethnic health disparities · 2025Review
- Social Determinants of Health and Early Brain Development.Pediatric clinics of North America · 2025Review
- The role of allostatic load in adverse pregnancy outcomes: a multisystem, developmental perspective.Frontiers in global women's health · 2025Review
- Association of allostatic load with functional disability in the China Health and Retirement Longitudinal Study.The journal of nutrition, health & aging · 2024Article
- Variation and correlates of psychosocial wellbeing among nulliparous women with preeclampsia.Pregnancy hypertension · 2024Article
- Examination of Maternal Allostatic Load Among Postpartum Women With Distinct Postpartum Symptom Typologies.Biological research for nursing · 2024Article
- The pivotal role of sleep in mediating the effects of life stressors and healthy habits on allostatic load in mid-life adults.Frontiers in human neuroscience · 2024Article
- Sleep, light exposure at night, and psychological wellbeing during pregnancy.BMC public health · 2023Article
- Trajectories in allostatic load as predictors of sleep quality among urban adults: Healthy aging in neighborhoods of diversity across the life span study.Sleep medicine · 2023Article
- Maternal Inflammation During Pregnancy and Offspring Brain Development: The Role of Mitochondria.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Review
- Minimally-invasive methods for examining biological changes in response to chronic stress: A scoping review.International journal of nursing studies · 2020Article
- Conceptualization, measurement, and effects of pregnancy-specific stress: review of research using the original and revised Prenatal Distress Questionnaire.Journal of behavioral medicine · 2020Review
- Multilevel Impact of Prenatal Risk and Protective Factors on Stress Biology and Infant Development: Study protocol of BABIP prospective birth cohort from Turkey.Brain, behavior, & immunity - health · 2020Article
- Review
- Sleep Disturbances and Modulations in Inflammation: Implications for Pregnancy Health.Social and personality psychology compass · 2019Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundAllostatic load (AL) measures the cumulative impact of chronic stress and is associated with adverse health outcomes. A novel scoring system has previously been developed for AL in early pregnancy that is associated with pre-eclampsia. It was hypothesized that AL, as identified by the present model, is associated with psychosocial stressors and, specifically, poor sleep quality.
methodsWomen were selected from a low-risk, community-dwelling study population who enrolled at <15 weeks gestation. Nine physiologic components were divided among the domains of cardiovascular, metabolic, and inflammatory function. Spearman's rank correlations were used to examine the association of AL with age, income, the Revised Prenatal Distress Questionnaire (NuPDQ), Inventory of Depressive Symptoms (IDS), and Pittsburgh Sleep Quality Index (PSQI). The Wilcoxon rank-sum test was used to compare AL by race and educational attainment.
resultsA total of 103 women were identified, with: a mean age of 29.8 ± 5.0 years, 17.5% black, and mean gestational age 12.2 ± 1.1 weeks. Allostatic load was positively correlated with the PSQI (ρ = 0.23, p = 0.018). There were no associations with age, income, prenatal distress, race, or depression scores. College-educated women had lower AL compared with those with less education (0.57 ± 0.43 vs 0.81 ± 0.55, p = 0.045).
conclusionHigher AL, measured by the pregnancy-specific model, was associated with poorer sleep quality and lower educational attainment, both of which were considered to be chronic stressors. These relationships were consistent with previous findings in non-pregnant populations, and suggest that AL may be useful for capturing the physiologic impact of chronic stress in early pregnancy.
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Registered trials
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