Evidence map›Paper›PMID 28449730›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2017

Hepatitis E and blood donation safety in selected European countries: a shift to screening?

Dragoslav Domanović, Richard Tedder, Johannes Blümel, Hans Zaaijer, Pierre Gallian, Christoph Niederhauser, Silvia Sauleda Oliveras, Joan O'Riordan, Fiona Boland, Lene Harritshøj and 9 more

Open access · diamondAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 1 pooled it
15.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 1 synthesis or guideline pooled it, 172 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Performance of Elecsys Anti-HEV IgG and IgM Assays for the Detection of Acute, Recent or Past Hepatitis E Virus Infection.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Transfusion-transmitted hepatitis E: What we know so far?World journal of gastroenterology · 2022
    Review
  18. Review
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 12 institutions in 10 countries.

Dragoslav DomanovićEuropean Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Richard TedderHepatitis E Study Group, Joint PHE/NHSBT Blood Borne Virus Unit, PHE, Colindale, London, United Kingdom.
Johannes BlümelPaul-Ehrlich-Institute, Federal Institute for Vaccines and Biomedicines, Virus Safety Section, Langen, Germany.
Hans ZaaijerSanquin, Blood-borne Infections & AMC, Clinical Virology, Amsterdam, the Netherlands.
Pierre GallianEtablissement Français du Sang, Saint-Denis, France.
Christoph NiederhauserInterregionale Blood Transfusion SRC, Berne, Switzerland.
Silvia Sauleda OliverasTransfusion Safety Laboratory, Banc de Sang i Teixits, Barcelona, Catalonia, Spain.
Joan O'RiordanIrish Blood Transfusion Service, Dublin, Ireland.
Fiona BolandIrish Blood Transfusion Service, Dublin, Ireland.
Lene HarritshøjRigshospitalet, Department of Clinical Immunology, Copenhagen, Denmark.
Maria São José NascimentoUniversity of Porto, Faculty of Pharmacy, Porto, Portugal.
Anna Rita CiccaglioneNational Health Institute, Viral Hepatitis Division, Department of Infectious Diseases, Rome, Italy.
Constatina PolitisHellenic Coordinating Haemovigilance Centre, Athens, Greece.
Cornelia AdlhochEuropean Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Benoit FlanLFB Biomedicaments, Biological Safety Surveillance, Courtaboeuf Cedex, France.
Wahiba Oualikene-GoninAgence nationale de sécurité du médicament et des produits de santé, Saint-Denis Cedex, France.
Guy RautmannEuropean Directorate for the Quality of Medicines and HealthCare, Strasbourg, France.
Paul StrengersInternational Plasma Fractionation Association, Amsterdam, Netherlands.
Patricia HewittNHS Blood and Transplant, London, United Kingdom.
European Centre for Disease Prevention and Control · SEIrish Blood Transfusion Service · IENHS Blood and Transplant · GBAgence Nationale de Sécurité du Médicament et des Produits de Santé · FRAtria · NLBanc de Sang i Teixits · ESÉtablissement Français du Sang · FRPaul Ehrlich Institut · DERigshospitalet · DKSanquin · NLSwiss Red Cross · CHUniversidade do Porto · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The public health implications of hepatitis E virus (HEV) in Europe have changed due to increasing numbers of hepatitis E cases and recent reports of chronic, persistent HEV infections associated with progression to cirrhosis in immunosuppressed patients. The main infectious risk for such immunosuppressed patients is exposure to undercooked infected pork products and blood transfusion. We summarised the epidemiology of HEV infections among blood donors and also outlined any strategies to prevent transfusion-transmitted HEV, in 11 European countries. In response to the threat posed by HEV and related public and political concerns, most of the observed countries determined seroprevalence of HEV in donors and presence of HEV RNA in blood donations. France, Germany, Spain and the United Kingdom (UK) reported cases of transfusion-transmitted HEV. Ireland and the UK have already implemented HEV RNA screening of blood donations; the Netherlands will start in 2017. Germany and France perform screening for HEV RNA in several blood establishments or plasma donations intended for use in high-risk patients respectively and, with Switzerland, are considering implementing selective or universal screening nationwide. In Greece, Portugal, Italy and Spain, the blood authorities are evaluating the situation. Denmark decided not to implement the HEV screening of blood donations.

Indexed as

Blood DonorsBlood SafetyBlood TransfusionEuropeHepatitis EHepatitis E virusHumansMass ScreeningRNA, ViralSeroepidemiologic StudiesTransfusion ReactionRNA, Viralblood donationhepatitis E virusscreeningtransfusiontransmission

Identifiers

PMID28449730
PMCPMC5404480
OpenAlexW2607889826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.