Evidence map›Paper›PMID 28449707›Full record

ArticleActa neuropathologica communications2017

Altered Ca

Franc Llorens, Katrin Thüne, Beata Sikorska, Matthias Schmitz, Waqas Tahir, Natalia Fernández-Borges, Maria Cramm, Nadine Gotzmann, Margarita Carmona, Nathalie Streichenberger and 11 more

Open access · goldAbstract read
In one paragraph

Article in Acta neuropathologica communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Post-translational modifications in prion diseases.Frontiers in molecular neuroscience · 2024
    Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Ppt1-deficiency dysregulates lysosomal CaJournal of inherited metabolic disease · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. An Update on Autophagy in Prion Diseases.Frontiers in bioengineering and biotechnology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 7 institutions in 4 countries.

Franc LlorensDepartment of Neurology, University Medical Center Göttingen, and German Center for Neurodegenerative Diseases (DZNE), Robert Koch Strasse 40, 37075, Göttingen, Germany. franc.llorens@gmail.com.
Katrin ThüneDepartment of Neurology, University Medical Center Göttingen, and German Center for Neurodegenerative Diseases (DZNE), Robert Koch Strasse 40, 37075, Göttingen, Germany.
Beata SikorskaDepartment of Molecular Pathology and Neuropathology, Medical University of Lodz, Lodz, Poland.
Matthias SchmitzDepartment of Neurology, University Medical Center Göttingen, and German Center for Neurodegenerative Diseases (DZNE), Robert Koch Strasse 40, 37075, Göttingen, Germany.
Waqas TahirDepartment of Neurology, University Medical Center Göttingen, and German Center for Neurodegenerative Diseases (DZNE), Robert Koch Strasse 40, 37075, Göttingen, Germany.
Natalia Fernández-BorgesCentro de Investigación en Sanidad Animal (CISA-INIA), Madrid, Spain.
Maria CrammDepartment of Neurology, University Medical Center Göttingen, and German Center for Neurodegenerative Diseases (DZNE), Robert Koch Strasse 40, 37075, Göttingen, Germany.
Nadine GotzmannDepartment of Neurology, University Medical Center Göttingen, and German Center for Neurodegenerative Diseases (DZNE), Robert Koch Strasse 40, 37075, Göttingen, Germany.
Margarita CarmonaInstitute of Neuropathology, IDIBELL-University Hospital Bellvitge, University of Barcelona, Hospitalet de Llobregat, Spain.
Nathalie StreichenbergerPrion Disease Laboratory, Pathology and Biochemistry, Groupement Hospitalier Est, Hospices Civils de Lyon/Claude Bernard University, Lyon, France.
Uwe MichelDepartment of Neurology, University Medical Center Göttingen, and German Center for Neurodegenerative Diseases (DZNE), Robert Koch Strasse 40, 37075, Göttingen, Germany.
Saima ZafarDepartment of Neurology, University Medical Center Göttingen, and German Center for Neurodegenerative Diseases (DZNE), Robert Koch Strasse 40, 37075, Göttingen, Germany.
Anna-Lena SchuetzGerman Center for Neurodegenerative Diseases (DZNE), Computational Systems Biology, Site Göttingen, Germany.
Ashish RajputGerman Center for Neurodegenerative Diseases (DZNE), Computational Systems Biology, Site Göttingen, Germany.
Olivier AndréolettiInstitut National de la Recherche Agronomique/Ecole Nationale Vétérinaire, Toulouse, France.
Stefan BonnGerman Center for Neurodegenerative Diseases (DZNE), Computational Systems Biology, Site Göttingen, Germany.
Andre FischerGerman Center for Neurodegenerative Diseases (DZNE), Epigenetics and Systems Medicine in Neurodegenerative Diseases, Site Göttingen, Germany.
Pawel P LiberskiDepartment of Molecular Pathology and Neuropathology, Medical University of Lodz, Lodz, Poland.
Juan Maria TorresCentro de Investigación en Sanidad Animal (CISA-INIA), Madrid, Spain.
Isidre FerrerCIBERNED (Network center for biomedical research of neurodegenerative diseases), Institute Carlos III, Ministry of Health, Madrid, Spain.
Inga ZerrDepartment of Neurology, University Medical Center Göttingen, and German Center for Neurodegenerative Diseases (DZNE), Robert Koch Strasse 40, 37075, Göttingen, Germany.
German Center for Neurodegenerative Diseases · DEUniversitätsmedizin Göttingen · DEBellvitge University Hospital · ESCentro de Investigación en Sanidad AnimalMedical University of Lodz · PLÉcole Nationale Vétérinaire de Toulouse · FRUniversité Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sporadic Creutzfeldt-Jakob disease (sCJD) is the most prevalent form of human prion disease and it is characterized by the presence of neuronal loss, spongiform degeneration, chronic inflammation and the accumulation of misfolded and pathogenic prion protein (PrP

Indexed as

AnimalsBrainCalciumCalpainCathepsinsCations, DivalentCells, CulturedCreutzfeldt-Jakob SyndromeDisease Models, AnimalHomeostasisHumansLysosomesMesocricetusMice, TransgenicNeuronsPrPSc ProteinsCalciumCalpainCathepsinsCations, DivalentPrPSc ProteinsRecombinant ProteinsCa2+CalciumCalpainCathepsinCreutzfeldt-Jakob diseasePrion protein

Identifiers

PMID28449707
PMCPMC5408381
OpenAlexW2609645441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.