ArticleMaternal & child nutrition2018
Iron status, body size, and growth in the first 2 years of life.
Article in Maternal & child nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 46 citations in OpenAlex.
- Reticulocyte hemoglobin equivalent as a diagnostic parameter of iron deficiency anemia in infants age 1-4 months.Archives of medical science : AMS · 2026Article
- Barriers to Healthy Eating and Influences on the Dietary Patterns and Eating Behaviours of 18-36-Month-Old Children in Ireland.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025Article
- Influence of Biological Sex and Congenital Iron Deficiency on Neonatal Cytokine Responses.Nutrients · 2024Article
- The Association of Infant Birth Sizes and Anemia under Five Years Old: A Population-Based Prospective Cohort Study in China.Nutrients · 2024Article
- Article
- Multivariate linear mixture models for the prediction of febrile seizure risk and recurrence: a prospective case-control study.Scientific reports · 2023Article
- Gut microbiota bridges the iron homeostasis and host health.Science China. Life sciences · 2023Review
- Wealth related inequality in women and children malnutrition in the state of Chhattisgarh and Tamil Nadu.BMC nutrition · 2022Article
- Article
- Reply to I Potani et al.Advances in nutrition (Bethesda, Md.) · 2022Article
- Child linear growth trajectories during the first three years of life in relation to infant iron status: a prospective cohort study in rural Vietnam.BMC nutrition · 2022Article
- Iron deficiency anemia in infants in Sousa (PB), Brazil: an association with nutritional status.Revista da Associacao Medica Brasileira (1992) · 2022Observational
- Article
- Anaemia among under-five children: Is maternal marriage at 18th birthday and above protective? Evidence from 15 countries in Sub-Saharan Africa.Maternal & child nutrition · 2021Article
- Factors associated with childhood anaemia in Afro-descendant communities in Alagoas, Brazil.Public health nutrition · 2021Article
- Iron status, body size, and growth in the first 2 years of life.Maternal & child nutrition · 2018Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rapid growth in infancy has been shown to adversely affect iron status up to 1 year; however the effect of growth on iron status in the second year of life has been largely unexplored. We aimed to investigate the impact of growth and body size in the first 2 years on iron status at 2 years. In the prospective, maternal-infant Cork BASELINE Birth Cohort Study, infant weight and length were measured at birth, 2, 6, 12, and 24 months and absolute weight (kg) and length (cm) gain from 0 to 2, 0 to 6, 0 to 12, 6 to 12, 12 to 24, and 0 to 24 months were calculated. At 2 years (n = 704), haemoglobin, mean corpuscular volume, and serum ferritin (umbilical cord concentrations also) were measured. At 2 years, 5% had iron deficiency (ferritin < 12 μg/L) and 1% had iron deficiency anaemia (haemoglobin < 110 g/L + ferritin < 12 μg/L). Weight gain from 6 to 12, 0 to 24, and 12 to 24 months were all inversely associated with ferritin concentrations at 2 years but only the association with weight gain from 12 to 24 months was robust after adjustment for potential confounders including cord ferritin (adj. estimate 95% CI: -4.40 [-8.43, -0.37] μg/L, p = .033). Length gain from 0 to 24 months was positively associated with haemoglobin at 2 years (0.42 [0.07, 0.76] g/L, p = .019), only prior to further adjustment for cord ferritin. To conclude, weight gain in the second year was inversely associated with iron stores at 2 years, even after accounting for iron status at birth. Further examinations of iron requirements, dietary intakes, and growth patterns in children in the second year of life in high-resource settings are warranted.
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