Evidence map›Paper›PMID 28449115›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2017

Estimation of State-Level Prevalence of Hepatitis C Virus Infection, US States and District of Columbia, 2010.

Eli S Rosenberg, Eric W Hall, Patrick S Sullivan, Travis H Sanchez, Kimberly A Workowski, John W Ward, Deborah Holtzman

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Viral Hepatitis Surveillance in the United States: Then, Now, and Looking Forward.Public health reports (Washington, D.C. : 1974) · 2025
    Article
  4. Article
  5. Hepatitis C Surveillance in the United States: Past, Present, and Future.Public health reports (Washington, D.C. : 1974) · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Liver Injury Increases the Incidence of HCC following AAV Gene Therapy in Mice.Molecular therapy : the journal of the American Society of Gene Therapy · 2021
    Article
  11. Article
  12. The Geography of Opioid Use Disorder: A Data Triangulation Approach.Infectious disease clinics of North America · 2020
    Review
  13. Observational
  14. Risk ofCancer prevention research (Philadelphia, Pa.) · 2019
    Article
  15. Article
  16. Article
  17. Article
  18. The Epidemiology of Hepatocellular Carcinoma in the USA.Current gastroenterology reports · 2019
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Eli S RosenbergDepartment of Epidemiology, Emory University Rollins School of Public Health.
Eric W HallDepartment of Epidemiology, Emory University Rollins School of Public Health.
Patrick S SullivanDepartment of Epidemiology, Emory University Rollins School of Public Health.
Travis H SanchezDepartment of Epidemiology, Emory University Rollins School of Public Health.
Kimberly A WorkowskiDivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine; and.
John W WardDivision of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia.
Deborah HoltzmanDivision of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia.
Emory University · USNational Center for HIV/AIDS Viral Hepatitis STD and TB Prevention · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND.: Hepatitis C virus (HCV) infection is the most common chronic blood-borne infection in the United States and a leading cause of morbidity and mortality. Previous analyses of the US National Health and Nutrition Examination Survey (NHANES) indicated approximately 3.6 million noninstitutionalized persons with antibody to HCV (anti-HCV). However, state-level prevalence remains less understood and cannot be estimated reliably from NHANES alone. METHODS.: We used 3 publicly available government data sources to estimate anti-HCV prevalence in each US state among noninstitutionalized persons aged ≥18 years. A small-area estimation model combined indirect standardization of NHANES-based prevalence with logistic regression modeling of mortality data, listing acute or chronic HCV infection as a cause of death, from the National Vital Statistics System during 1999-2012. Model results were combined with US Census population sizes to estimate total number and prevalence of persons with antibody to HCV in 2010. RESULTS.: National anti-HCV prevalence was 1.67% (95% confidence interval [CI], 1.53-1.90), or 3 911 800 (95% CI, 3 589 400- 4 447 500) adults in 2010. State-specific prevalence ranged from 0.71% (Illinois) to 3.34% (Oklahoma). The West census region had the highest region-specific prevalence (2.14% [95% CI, 1.96-2.48]); 10 of 13 states had rates above the national average. The South had the highest number of persons with anti-HCV (n = 1561600 [95% CI, 1 427 700-1 768 900]). The Midwest had the lowest region-specific prevalence (1.14% [95% CI, 1.04%-1.30%]). CONCLUSIONS.: States in the US West and South have been most impacted by hepatitis C. Estimates of HCV infection burden are essential to guide policy and programs to optimally prevent, detect, and cure infection.

Indexed as

AdultAgedDistrict of ColumbiaEpidemiological MonitoringFemaleHepacivirusHepatitis CHepatitis C AntibodiesHepatitis C, ChronicHumansLogistic ModelsMaleMiddle AgedNutrition SurveysPrevalenceRisk FactorsHepatitis C AntibodiesRNA, Viralhepatitis CNational Health and Nutrition Examination SurveyNational Vital Statistics System.prevalencesurveillance

Identifiers

PMID28449115
PMCPMC5434341
OpenAlexW2608099740

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.