ArticleInternational journal of epidemiology2017
Oral health and mortality in the Golestan Cohort Study.
Article in International journal of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Impact of Oral Hygiene Practices in Reducing Cardiometabolic Risk, Incidence, and Mortality: A Systematic Review.International journal of environmental research and public health · 2024Pooled it
- Lower Number of Teeth Is Related to Higher Risks for ACVD and Death-Systematic Review and Meta-Analyses of Survival Data.Frontiers in cardiovascular medicine · 2021Pooled it
- Could periodontitis be associated with overall and cancer-specific mortality risk; a 35-year Swedish cohort study.Acta odontologica Scandinavica · 2025Article
- Association between the number of teeth and all-cause mortality rate in the MASHAD Cohort Study.Journal of dental research, dental clinics, dental prospects · 2025Article
- Association between tooth loss and geriatric syndromes in older adults: a cohort study from a rural area in eastern China.Aging clinical and experimental research · 2025Article
- Lip and oral cavity cancer in Iran from 1990 to 2019 based on the global burden of disease study.Scientific reports · 2025Article
- Malocclusion Worsens Survival Following Sepsis Due to the Disruption of Innate and Acquired Immunity.International journal of molecular sciences · 2025Article
- Global Research Trends in the Links between Periodontal Disease and Cancer: A Bibliometric Analysis.Pathogens (Basel, Switzerland) · 2024Review
- Association of oral health with all-cause and cause-specific mortality in older Chinese adults: A 14-year follow-up of the Guangzhou Biobank Cohort study.Journal of global health · 2024Article
- Effects of oral health-related quality of life on total mortality: a prospective cohort study.BMC oral health · 2023Article
- Sex and smoking differences in the association between gastroesophageal reflux and risk of esophageal squamous cell carcinoma in a high-incidence area: Golestan Cohort Study.International journal of cancer · 2023Article
- Tooth loss, denture use, and all-cause and cause-specific mortality in older adults: a community cohort study.Frontiers in public health · 2023Article
- Frailty mediated the association between tooth loss and mortality in the oldest old individuals: a cohort study.Frontiers in public health · 2023Article
- Tooth count, untreated caries and mortality in US adults: a population-based cohort study.International journal of epidemiology · 2022Article
- Combined association of cognitive impairment and poor oral health on mortality risk in older adults: Results from the NHANES with 15 years of follow-up.Journal of periodontology · 2022Article
- Associations of periodontal disease and tooth loss with all-cause and cause-specific mortality in the Sister Study.Journal of clinical periodontology · 2021Article
- Oral Health Determinants among Opium Users in Kerman, Iran.Addiction & health · 2021Article
- Oral Health and Risk of Upper Gastrointestinal Cancers in a Large Prospective Study from a High-risk Region: Golestan Cohort Study.Cancer prevention research (Philadelphia, Pa.) · 2021Article
- The profile of Rafsanjan Cohort Study.European journal of epidemiology · 2021Article
- Mortality-and Health-Related Factors in a Community-Dwelling of Oldest-Older Adults at the Age of 90: A 10-Year Follow-Up Study.International journal of environmental research and public health · 2020Article
Corrections and comments
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Authors and funding
14 authors at 9 institutions in 3 countries.
Funding
Abstract
Background: Previous studies have found associations between oral health and mortality, but the majority of previous studies have been conducted in high-income countries. Methods: We used data from the Golestan Cohort Study, a study of 50 045 people aged 40 to 75 years in north eastern Iran, recruited from January 2004 to June 2008. Tooth loss and decayed, missing and filled teeth (DMFT) were assessed by trained physicians. Frequency of tooth brushing and use of dentures were self-reported. Cause-specific mortality was ascertained through March 2014. We calculated hazard ratios (HRs) and 95% confidence intervals (95% CIs) for the associations between the oral health variables, overall mortality and cause-specific mortality. Results: Participants with the greatest tooth loss had increased overall mortality (HR 1.43; 95% CI: 1.28, 1.61) compared with those with the least tooth loss; similar estimates were observed for DMFT score. For cause-specific mortality, an increased risk of death was found for tooth loss and mortality from cardiovascular disease (HR 1.33; 95% CI: 1.13, 1.56), cancer (HR 1.30; 95% CI: 1.03, 1.65) and injuries (HR 1.99; 95% CI: 1.28, 3.09). The associations between oral health and injury mortality were strongly attenuated after exclusion of participants with comorbid conditions at baseline. No statistical interaction was found between denture use and tooth loss or DMFT on mortality. Conclusions: Poor oral health appears to predict overall and cause-specific mortality in populations in economic transition. Investigation of the underlying mechanisms might provide an important contribution to reducing mortality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.