Evidence map›Paper›PMID 28449007›Full record

ArticleBritish journal of cancer2017

Efficacy of stereotactic body radiotherapy in oligorecurrent and in oligoprogressive prostate cancer: new evidence from a multicentric study.

Luca Triggiani, Filippo Alongi, Michela Buglione, Beatrice Detti, Riccardo Santoni, Alessio Bruni, Ernesto Maranzano, Frank Lohr, Rolando D'Angelillo, Alessandro Magli and 10 more

Registry-linked trialOpen access · hybridAbstract readMulticenter Study
In one paragraph

Article in British journal of cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06489821 (STereotactic Body Radiotherapy), which is not on this map. Cited by 82 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 1 pooled it
15.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06489821 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

STereotactic Body Radiotherapy (SBRT) After oligoprogRession Metastatic Breast Cancer (STAR-B)

TypeinterventionalSponsorJuravinski Cancer CenterRan2024 to 2027Enrolled36ConditionsMetastatic Breast Cancer, OligoprogressionArmsStereotactic body radiotherapy
3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 1 synthesis or guideline pooled it, 147 citations in OpenAlex.

  1. Pooled it
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  9. Outcomes of Radiotherapy in Oligoprogressive Breast Cancer.Journal of personalized medicine · 2024
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  14. Stereotactic body radiotherapy results forReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2024
    Article
  15. Stereotactic ablative radiotherapy (SABR) for pelvic nodal oligorecurrence in prostate cancer.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2024
    Article
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  20. Unravelling oligometastatic disease from the perspective of radiation and medical oncology. Part II: prostate cancer and colorectal cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Article

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 9 institutions in 1 country.

Luca TriggianiDepartment of Radiation Oncology, University and Spedali Civili Hospital, Brescia, Italy.
Filippo AlongiDepartment of Radiation Oncology, Sacro Cuore Don Calabria Cancer Care Center, Negrar-Verona, Italy.
Michela BuglioneDepartment of Radiation Oncology, University and Spedali Civili Hospital, Brescia, Italy.
Beatrice DettiDepartment of Radiation Oncology, A.O.U Careggi, University of Florence, Florence, Italy.
Riccardo SantoniDepartment of Radiation Oncology, Policlinico Tor Vergata, University of Rome, Rome, Italy.
Alessio BruniDepartment of Radiation Oncology, AOU Policlinico Modena, Modena, Italy.
Ernesto MaranzanoDepartment of Radiation Oncology, 'S. Maria' Hospital, Terni, Italy.
Frank LohrDepartment of Radiation Oncology, AOU Policlinico Modena, Modena, Italy.
Rolando D'AngelilloDepartment of Radiation Oncology, Campus Biomedico University, Rome, Italy.
Alessandro MagliDepartment of Radiation Oncology, 'Santa Maria della Misericordia' Hospital, Udine, Italy.
Alberto BonettaDepartment of Radiation Oncology, Cremona Hospital, Cremona, Italy.
Rosario MazzolaDepartment of Radiation Oncology, Sacro Cuore Don Calabria Cancer Care Center, Negrar-Verona, Italy.
Nadia PasinettiDepartment of Radiation Oncology, University and Spedali Civili Hospital, Brescia, Italy.
Giulio FrancoliniDepartment of Radiation Oncology, A.O.U Careggi, University of Florence, Florence, Italy.
Gianluca IngrossoDepartment of Radiation Oncology, Policlinico Tor Vergata, University of Rome, Rome, Italy.
Fabio TrippaDepartment of Radiation Oncology, 'S. Maria' Hospital, Terni, Italy.
Sergio FersinoDepartment of Radiation Oncology, Sacro Cuore Don Calabria Cancer Care Center, Negrar-Verona, Italy.
Paolo BorghettiDepartment of Radiation Oncology, University and Spedali Civili Hospital, Brescia, Italy.
Paolo GhirardelliDepartment of Radiation Oncology, University and Spedali Civili Hospital, Brescia, Italy.
Stefano Maria MagriniDepartment of Radiation Oncology, University and Spedali Civili Hospital, Brescia, Italy.
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITOspedale Sacro Cuore Don Calabria · ITPoliclinico di Modena · ITPoliclinico Tor Vergata · ITSanta Maria Nuova Hospital · ITUniversity of Florence · ITIstituti Ospitalieri di Cremona · ITOspedale Santa Maria della Misericordia di Udine · ITUniversità Campus Bio-Medico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of the present study is to evaluate the impact of metastases-directed stereotactic body radiotherapy in two groups of oligometastatic prostate cancer (PC) patients: oligorecurrent PC and oligoprogressive castration-resistant PC (oligo-CRPC).

methodsInclusion criteria of the present multicentre retrospective analysis were: (1) oligorecurrent PC, defined as the presence of 1-3 lesions (bone or nodes) detected with choline positron emission tomography or CT plus bone scan following biochemical recurrence; (2) oligo-CRPC, defined as metastases (bone or nodes) detected after a prostatic-specific antigen rise during androgen deprivation therapy (ADT). Primary end points were: distant progression-free survival (DPFS) and ADT-free survival in oligorecurrent PC patients; DPFS and second-line systemic treatment-free survival in oligo-CRPC patients.

resultsAbout 100 patients with oligorecurrent PC (139 lesions) and 41 with oligo-CRPC (70 lesions), treated between March 2010 and April 2016, were analysed. After a median follow-up of 20.4 months, in the oligorecurrent group 1- and 2-year DPFS were 64.4 and 43%. The rate of LC was 92.8% at 2 years. At a median follow-up of 23.4 months, in the oligo-CRPC group 1- and 2-year DPFS were 43.2 and 21.6%. Limitations include the retrospective design.

conclusionsStereotactic body radiotherapy seems to be a useful treatment both for oligorecurrent and oligo-CRPC.

Indexed as

RadiosurgeryAgedAged, 80 and overAndrogen AntagonistsBone NeoplasmsDisease-Free SurvivalDisease ProgressionFeasibility StudiesHumansLymphatic MetastasisMaleMiddle AgedNeoplasm Recurrence, LocalPositron-Emission TomographyProstatectomyProstate-Specific AntigenAndrogen AntagonistsProstate-Specific Antigen

Identifiers

PMID28449007
PMCPMC5518848
OpenAlexW2608885567

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LicenceCC BY-NC-SA
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.