Evidence map›Paper›PMID 28448767›Full record

ArticleTranscription2017

Transcriptional control of yeast ribosome biogenesis: A multifaceted role for general regulatory factors.

Maria Cristina Bosio, Beatrice Fermi, Giorgio Dieci

Open access · bronzeAbstract read
In one paragraph

Article in Transcription, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Eukaryotic RNA Polymerases: The Many Ways to Transcribe a Gene.Frontiers in molecular biosciences · 2021
    Review
  7. The medium-size noncoding RNA transcriptome ofNAR genomics and bioinformatics · 2020
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Maria Cristina Bosioa Department of Chemistry , Life Sciences and Environmental Sustainability, University of Parma , Parma , Italy.
Beatrice Fermia Department of Chemistry , Life Sciences and Environmental Sustainability, University of Parma , Parma , Italy.
Giorgio Diecia Department of Chemistry , Life Sciences and Environmental Sustainability, University of Parma , Parma , Italy.
University of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Saccharomyces cerevisiae, a group of more than 200 co-regulated genes (Ribi genes) is involved in ribosome biogenesis. This regulon has recently been shown to rely on a small set of transcriptional regulators (mainly Abf1, but also Reb1, Tbf1 and Rap1) previously referred to as general regulatory factors (GRFs) because of their widespread binding and action at many promoters and other specialized genomic regions. Intriguingly, Abf1 binding to Ribi genes is differentially modulated in response to distinct nutrition signaling pathways. Such a dynamic promoter association has the potential to orchestrate both activation and repression of Ribi genes in synergy with neighboring regulatory sites and through the functional interplay of histone acetyltransferases and deacetylases.

Indexed as

Gene Expression Regulation, FungalPromoter Regions, GeneticRibosomesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription, GeneticSaccharomyces cerevisiae ProteinsAbf1histone acetylationRap1Reb1Ribi genesRpd3 histone deacetylaseTbf1

Identifiers

PMID28448767
PMCPMC5574525
OpenAlexW2608749329

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.