ArticlePloS one2017
A minimal model of burst-noise induced bistability.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed.
- Self-Regulated Symmetry Breaking Model for Stem Cell Differentiation.Entropy (Basel, Switzerland) · 2023Article
- Network location and clustering of genetic mutations determine chronicity in a stylized model of genetic diseases.Scientific reports · 2022Article
- A tightly regulated and adjustable CRISPR-dCas9 based AND gate in yeast.Nucleic acids research · 2019Article
- Analysis of stochastic bifurcations with phase portraits.PloS one · 2018Article
- Role of noise and parametric variation in the dynamics of gene regulatory circuits.NPJ systems biology and applications · 2018Article
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3 authors.
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Abstract
We investigate the influence of intrinsic noise on stable states of a one-dimensional dynamical system that shows in its deterministic version a saddle-node bifurcation between monostable and bistable behaviour. The system is a modified version of the Schlögl model, which is a chemical reaction system with only one type of molecule. The strength of the intrinsic noise is varied without changing the deterministic description by introducing bursts in the autocatalytic production step. We study the transitions between monostable and bistable behavior in this system by evaluating the number of maxima of the stationary probability distribution. We find that changing the size of bursts can destroy and even induce saddle-node bifurcations. This means that a bursty production of molecules can qualitatively change the dynamics of a chemical reaction system even when the deterministic description remains unchanged.
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