ArticlePloS one2017
Characterization of the fecal microbiome during neonatal and early pediatric development in puppies.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed.
- Randomised controlled trial finds no evidence that a synbiotic improves health in assistance dog puppies.The Veterinary record · 2026Article
- Development of the Urogenital Microbiota in Healthy Beagle Puppies: A Longitudinal Comparison with the Dam.Life (Basel, Switzerland) · 2026Article
- Neonatal Gut Microbiota in Puppies and Kittens: From Maternal Transmission to Immune Development.Animals : an open access journal from MDPI · 2026Review
- Longitudinal study of diet digestibility, microbiome, and gut fermentation metabolites in growing dogs.Journal of veterinary internal medicine · 2026Article
- The perinatal microbiota in dogs and cats: a narrative review from human research to veterinary practice.Frontiers in veterinary science · 2026Review
- The gut microbiota of Labrador retriever puppies: a longitudinal cohort study.Animal microbiome · 2025Article
- A NovelMicroorganisms · 2025Article
- Age-related changes in growth and fecal parameters, nutrient digestibility, hematology, and serum biochemistry of Beagle dogs.Journal of animal science and technology · 2025Article
- Understanding the diversity and roles of the canine gut microbiome.Journal of animal science and biotechnology · 2025Review
- The Impact of a Multi-Strain Probiotic Supplementation on Puppies Manifesting Diarrhoeic Symptoms During the Initial Seven Days of Life.Animals : an open access journal from MDPI · 2025Article
- Gut Microbiota Variation in Aging Dogs with Osteoarthritis.Animals : an open access journal from MDPI · 2025Article
- Microbiota Analysis and Characterisation of the NovelMicroorganisms · 2025Article
- Vaginal Seeding: Is There Any Positive Effect in Canine C-Sections?Animals : an open access journal from MDPI · 2025Article
- Metagenomic analyses of gut microbiome composition and function with age in a wild bird; little change, except increased transposase gene abundance.ISME communications · 2025Article
- Oral microbiota in cesarean-delivered puppies.Frontiers in veterinary science · 2025Article
- Deciphering T Cell Dynamics in Alzheimer's Disease Pathogenesis: Insights and Implications.Current neuropharmacology · 2025Review
- Meconium microbiota in naturally delivered canine puppies.BMC veterinary research · 2024Article
- Fewer culturable Lactobacillaceae species identified in faecal samples of pigs performing manipulative behaviour.Scientific reports · 2024Article
- Validation of method for faecal sampling in cats and dogs for faecal microbiome analysis.BMC veterinary research · 2023Article
- Composition and evolution of the gut microbiota of growing puppies is impacted by their birth weight.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Limited information is available describing the development of the neonatal fecal microbiome in dogs. Feces from puppies were collected at 2, 21, 42, and 56 days after birth. Feces were also collected from the puppies' mothers at a single time point within 24 hours after parturition. DNA was extracted from fecal samples and 454-pyrosequencing was used to profile 16S rRNA genes. Species richness continued to increase significantly from 2 days of age until 42 days of age in puppies. Furthermore, microbial communities clustered separately from each other at 2, 21, and 42 days of age. The microbial communities belonging to dams clustered separately from that of puppies at any given time point. Major phylogenetic changes were noted at all taxonomic levels with the most profound changes being a shift from primarily Firmicutes in puppies at 2 days of age to a co-dominance of Bacteroidetes, Fusobacteria, and Firmicutes by 21 days of age. Further studies are needed to elucidate the relationship between puppy microbiota development, physiological growth, neonatal survival, and morbidity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.