Evidence map›Paper›PMID 28447789›Full record

ArticleJournal of medicinal chemistry2017

Exploring the Role of N

Riccardo Petrelli, Mirko Scortichini, Sonja Kachler, Serena Boccella, Carmen Cerchia, Ilaria Torquati, Fabio Del Bello, Daniela Salvemini, Ettore Novellino, Livio Luongo and 5 more

Open access · greenAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Synthesis,Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
    Article
  3. Adenosine receptors as promising targets for the management of ocular diseases.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2021
    Review
  4. Article
  5. Article
  6. Article
  7. Design and in Vivo Characterization of AJournal of medicinal chemistry · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Riccardo PetrelliSchool of Pharmacy, Medicinal Chemistry Unit, University of Camerino , Via S. Agostino 1, 62032 Camerino, Italy.
Mirko ScortichiniSchool of Pharmacy, Medicinal Chemistry Unit, University of Camerino , Via S. Agostino 1, 62032 Camerino, Italy.
Sonja KachlerInstitut für Pharmakologie and Toxikologie, Universität Würzburg , D-97078 Würzburg, Germany.
Serena BoccellaSection of Pharmacology "L. Donatelli", Department of Experimental Medicine, University of Campania "L. Vanvitelli" , 80138 Naples, Italy.
Carmen CerchiaDepartment of Pharmacy, "Drug Discovery" Laboratory, University of Naples Federico II , 80131 Naples, Italy.
Ilaria TorquatiSchool of Pharmacy, Medicinal Chemistry Unit, University of Camerino , Via S. Agostino 1, 62032 Camerino, Italy.
Fabio Del BelloSchool of Pharmacy, Medicinal Chemistry Unit, University of Camerino , Via S. Agostino 1, 62032 Camerino, Italy.
Daniela SalveminiDepartment of Pharmacology and Physiology, Saint Louis University School of Medicine , St. Louis, Missouri 63104, United States.
Ettore NovellinoDepartment of Pharmacy, "Drug Discovery" Laboratory, University of Naples Federico II , 80131 Naples, Italy.
Livio LuongoSection of Pharmacology "L. Donatelli", Department of Experimental Medicine, University of Campania "L. Vanvitelli" , 80138 Naples, Italy.
Sabatino MaioneSection of Pharmacology "L. Donatelli", Department of Experimental Medicine, University of Campania "L. Vanvitelli" , 80138 Naples, Italy.
Kenneth A JacobsonLaboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , Bethesda, Maryland 20892, United States.ORCID 0000-0001-8104-1493
Antonio LavecchiaDepartment of Pharmacy, "Drug Discovery" Laboratory, University of Naples Federico II , 80131 Naples, Italy.
Karl-Norbert KlotzInstitut für Pharmakologie and Toxikologie, Universität Würzburg , D-97078 Würzburg, Germany.
Loredana CappellacciSchool of Pharmacy, Medicinal Chemistry Unit, University of Camerino , Via S. Agostino 1, 62032 Camerino, Italy.ORCID 0000-0001-8155-7211
Università di Camerino · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Naples Federico II · ITUniversity of Würzburg · DENational Institutes of Health · USSaint Louis University · US

Funding

Development Of Drugs Acting At Adenosine ReceptorsZIADK031117 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI JACOBSON, KENNETH ALAN · 2009 to 2025
$10.4M
Intramural NIH HHS ZIA DK031117
6 · The paper itself

Abstract

Structural determinants of affinity of N

Indexed as

Acute PainAdenosineAdenosine A1 Receptor AgonistsAdenosine A3 Receptor AntagonistsAnalgesicsAnimalsHumansMiceModels, MolecularPurinergic P1 Receptor AgonistsPurinergic P1 Receptor AntagonistsReceptor, Adenosine A1Receptor, Adenosine A3Receptors, Purinergic P1AdenosineAdenosine A1 Receptor AgonistsAdenosine A3 Receptor AntagonistsAnalgesicsPurinergic P1 Receptor AgonistsPurinergic P1 Receptor AntagonistsReceptor, Adenosine A1Receptor, Adenosine A3Receptors, Purinergic P1

Identifiers

PMID28447789
PMCPMC5669264
OpenAlexW2609140791

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.