Evidence map›Paper›PMID 28447297›Full record

ArticleNeuroinformatics2017

Generating Neuron Geometries for Detailed Three-Dimensional Simulations Using AnaMorph.

Konstantin Mörschel, Markus Breit, Gillian Queisser

Abstract read
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In one paragraph

Article in Neuroinformatics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Modeling Neurons in 3D at the Nanoscale.Advances in experimental medicine and biology · 2022
    Article
  6. Article
  7. Article
  8. NeuroBox: Computational Mathematics in Multiscale Neuroscience.Computing And Visualization In Science · 2019
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Konstantin MörschelGoethe Center for Scientific Computing, Goethe University Frankfurt, Kettenhofweg 139, 60325, Frankfurt am Main, Germany.
Markus BreitGoethe Center for Scientific Computing, Goethe University Frankfurt, Kettenhofweg 139, 60325, Frankfurt am Main, Germany.
Gillian QueisserDepartment of Mathematics, Temple University, 1805 N Broad Street, Philadelphia, PA, 19122-6094, USA. gillian.queisser@temple.edu.ORCID http://orcid.org/0000-0003-4691-5276

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Generating realistic and complex computational domains for numerical simulations is often a challenging task. In neuroscientific research, more and more one-dimensional morphology data is becoming publicly available through databases. This data, however, only contains point and diameter information not suitable for detailed three-dimensional simulations. In this paper, we present a novel framework, AnaMorph, that automatically generates water-tight surface meshes from one-dimensional point-diameter files. These surface triangulations can be used to simulate the electrical and biochemical behavior of the underlying cell. In addition to morphology generation, AnaMorph also performs quality control of the semi-automatically reconstructed cells coming from anatomical reconstructions. This toolset allows an extension from the classical dimension-reduced modeling and simulation of cellular processes to a full three-dimensional and morphology-including method, leading to novel structure-function interplay studies in the medical field. The developed numerical methods can further be employed in other areas where complex geometries are an essential component of numerical simulations.

Indexed as

AlgorithmsComputer SimulationImaging, Three-DimensionalModels, NeurologicalAnimalsHumansNeurons3D simulationAnaMorphGeometric modelingNeuroMorpho.OrgNeuron reconstruction

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.