Evidence map›Paper›PMID 28447279›Full record

ReviewJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2017

Multi-modality molecular imaging of aortic aneurysms.

Brian J Malm, Mehran M Sadeghi

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Exploring Vessel Wall Biology In Vivo by Ultrasensitive Total-Body PET.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  6. Frontiers in cardiovascular medicine · 2023
    Article
  7. Evaluation of cardiac allograft vasculopathy by positron emission tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Review
  8. Iterative reconstruction incorporating background correction improves quantification of [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  9. Article
  10. Scintigraphic Imaging of Inflammation in the Aortic Wall UsingSovremennye tekhnologii v meditsine · 2021
    Article
  11. Article
  12. Current and novel radiopharmaceuticals for imaging cardiovascular inflammation.The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... · 2020
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Brian J MalmSection of Cardiovascular Medicine, Yale University School of Medicine, PO Box 208017, New Haven, CT, 06520, USA. brian.malm@yale.edu.
Mehran M SadeghiSection of Cardiovascular Medicine, Yale University School of Medicine, PO Box 208017, New Haven, CT, 06520, USA.
VA Connecticut Healthcare System · USYale University · US

Funding

Imaging protease activation in calcific aortic valve diseaseR01HL114703 · NHLBI · YALE UNIVERSITY · PI SADEGHI, MEHRAN M · 2012 to 2016
$2.0M
Macrophage elastase and its imaging in vascular inflammation and remodelingR01HL112992 · NHLBI · YALE UNIVERSITY · PI SADEGHI, MEHRAN M · 2013 to 2016
$2.0M
BLRD VA I01 BX001750NHLBI NIH HHS R01 HL112992NHLBI NIH HHS R01 HL114703
6 · The paper itself

Abstract

Aneurysms of the thoracic and abdominal aorta are common and can be associated with significant morbidity and mortality when complications, including dissection, rupture, or thrombosis, occur. Current approaches to diagnosis and risk stratification rely on measurements of aneurysm size and rate of growth, often using various imaging modalities, which may be suboptimal in identifying patients at the highest and lowest risk of complications. Targeting the biological processes underlying aneurysm formation and expansion with molecular imaging offers an exciting opportunity to characterize aortic aneurysms beyond size and address current gaps in our approach to diagnosis and treatment. In this review, we summarize the epidemiology and biology of aortic aneurysms and highlight the role of molecular imaging in furthering our understanding of aneurysm pathogenesis and its potential future role in guiding management.

Indexed as

Aortic AneurysmHumansMolecular ImagingMultimodal ImagingRisk AssessmentaneurysmFDGmatrix metalloproteinasesMolecular imagingPETSPECT

Identifiers

PMID28447279
PMCPMC7720418
OpenAlexW2609672356

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.