Evidence map›Paper›PMID 28447239›Full record

Trial reportBreast cancer research and treatment2017

The potential role of three-dimensional surface imaging as a tool to evaluate aesthetic outcome after Breast Conserving Therapy (BCT).

Rachel L O'Connell, Rosa Di Micco, Komel Khabra, Lisa Wolf, Nandita deSouza, Nicola Roche, Peter A Barry, Anna M Kirby, Jennifer E Rusby

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in Breast cancer research and treatment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. [Techniques enhancement for tissue expander/implant two-stage breast reconstruction].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2020
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Rachel L O'ConnellDepartment of Breast Surgery, The Royal Marsden NHS Foundation Trust, Orchard House, Downs Road, Sutton, SM2 5PT, UK.
Rosa Di MiccoDepartment of Breast Surgery, The Royal Marsden NHS Foundation Trust, Orchard House, Downs Road, Sutton, SM2 5PT, UK.
Komel KhabraDepartment of Statistics, The Royal Marsden NHS Foundation Trust, Sutton, UK.
Lisa WolfDepartment of Breast Surgery, The Royal Marsden NHS Foundation Trust, Orchard House, Downs Road, Sutton, SM2 5PT, UK.
Nandita deSouzaCancer Research UK Cancer Imaging Centre, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, UK.
Nicola RocheDepartment of Breast Surgery, The Royal Marsden NHS Foundation Trust, Orchard House, Downs Road, Sutton, SM2 5PT, UK.
Peter A BarryDepartment of Breast Surgery, The Royal Marsden NHS Foundation Trust, Orchard House, Downs Road, Sutton, SM2 5PT, UK.
Anna M KirbyDepartment of Clinical Oncology, The Royal Marsden NHS Foundation Trust, Sutton, UK.
Jennifer E RusbyDepartment of Breast Surgery, The Royal Marsden NHS Foundation Trust, Orchard House, Downs Road, Sutton, SM2 5PT, UK. jennifer.rusby@rmh.nhs.uk.
Royal Marsden NHS Foundation Trust · GBFederico II University Hospital · ITInstitute of Cancer Research · GB

Funding

Cancer Research UK 16464Cancer Research UK 19727Medical Research Council G0701533
6 · The paper itself

Abstract

purposeTo establish whether objective measurements of symmetry of volume and shape using three-dimensional surface imaging (3D-SI) can be used as surrogate markers of aesthetic outcome in patients who have undergone breast conserving therapy (BCT).

methodsWomen who had undergone unilateral BCT in the preceding 1-6 years were invited to participate. Participants completed a satisfaction questionnaire (BREAST-Q) and underwent 3D-SI. Volume and surface symmetry were measured on the images. Assessment of aesthetic outcome was undertaken by a panel of clinicians. The Kruskal-Wallis test was used to assess the relationship between volume and shape symmetry measurements with the panel score. Spearman's rho correlations were used to assess the relationship between the measurements and patient satisfaction.

results200 women participated. Median volume symmetry was 87% (IQR 78-93) and shape symmetry was 5.9 mm (IQR 4.2-8.0). The participants were grouped according to panel assessment of aesthetic outcome (poor, fair, good, excellent) and the median volume and shape symmetry was calculated for each group. Volume symmetry significantly differed between the groups. Post hoc pairwise comparisons demonstrated that these differences existed between panel scores of fair versus good and good versus excellent. Median shape symmetry also differed according to patient panel groups with four significant pairwise comparisons between poor versus good, poor versus excellent, fair versus good and fair versus excellent. There was a significant but weak correlation of both volume symmetry and surface asymmetry with BREAST-Q scores (correlation coefficients 0.187 and -0.229, respectively).

conclusionBreast volume and shape symmetry are both associated with panel assessment scores and patient satisfaction. The objective volume and shape symmetry measures were strongly associated with panel assessment scores, such that a 3D-SI tool could replace panel assessment as a faster and more objective method of evaluating aesthetic outcomes.

Indexed as

Patient SatisfactionAgedBreast NeoplasmsFemaleHumansImaging, Three-DimensionalMammographyMastectomy, SegmentalMiddle AgedTreatment OutcomeAesthetic outcomeBreast cancerPatient reported outcome measures

Identifiers

PMID28447239
PMCPMC5487698
OpenAlexW2609646965

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.