Evidence map›Paper›PMID 28447066›Full record

ReviewNutrition and healthy aging2017

Neuronal functions of FOXO/DAF-16.

Sun Y Kim, Ashley E Webb

Open access · diamondAbstract readReview
In one paragraph

Review in Nutrition and healthy aging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. [Bushen Yijing Formula attenuates amyloid β-protein deposi-tion and oxidative damage inZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026
    Article
  4. Article
  5. Article
  6. Dendrobium Nobile Alcohol Extract Extends the Lifespan ofMolecules (Basel, Switzerland) · 2024
    Article
  7. Article
  8. FOXO inBiology · 2023
    Article
  9. Article
  10. Effect of FOXO3 and Air Pollution on Cognitive Function: A Longitudinal Cohort Study of Older Adults in China From 2000 to 2014.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  11. Article
  12. Article
  13. Insulin and Memory in Invertebrates.Frontiers in behavioral neuroscience · 2022
    Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. A panel of fluorophore-taggedmicroPublication biology · 2020
    Article
  20. FOXO Regulates Neuromuscular Junction Homeostasis DuringFrontiers in aging neuroscience · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sun Y KimDepartment of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, USA.
Ashley E WebbDepartment of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, USA.
Brown University · US

Funding

Predoctoral Training in the Molecular Biology of AgingT32AG041688 · NIA · BROWN UNIVERSITY · PI NICOLA NERETTI, John M Sedivy · 2012 to 2026
$3.5M
NIA NIH HHS T32 AG041688
6 · The paper itself

Abstract

The FOXO family of transcription factors plays a conserved role in longevity and tissue homeostasis across species. In the mammalian nervous system, emerging evidence has implicated FOXOs in cognitive performance, stem cell maintenance, regeneration, and protection against stress. Much of what we know about neuronal functions of FOXO emerged from recent studies in

Indexed as

agingbrainDAF-16FOXOinsulin/IGF signaling

Identifiers

PMID28447066
PMCPMC5389038
OpenAlexW2513464535

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.