Evidence map›Paper›PMID 28446943›Full record

ReviewCurrent cardiovascular imaging reports2017

The Updated NICE Guidelines: Cardiac CT as the First-Line Test for Coronary Artery Disease.

Alastair J Moss, Michelle C Williams, David E Newby, Edward D Nicol

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in Current cardiovascular imaging reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07140419 (A Prospective, Multicenter, Randomized Controlled Trial on the Impact of Coronary CTA Combined With CT-FFR on Diagnosis and Treatment Decisions and Clinical Outcomes in Emergency Patients With Intermediate Risk Chest Pain), which is not on this map. Cited by 145 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
145citing papers in PubMed, 1 pooled it
24.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07140419 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Prospective, Multicenter, Randomized Controlled Trial on the Impact of Coronary CTA Combined With CT-FFR on Diagnosis and Treatment Decisions and Clinical Outcomes in Emergency Patients With Intermediate Risk Chest Pain

TypeinterventionalSponsorQilu Hospital of Shandong UniversityRan2026 to 2032Enrolled2,000ConditionsChest Pain, Coronary Artery Disease, Emergency DepartmentArmsCoronary computed tomographic angiography with CT - derived fractional flow reserve
3 · Its place in the literature

Who cites it

145 citing papers in PubMed, 1 synthesis or guideline pooled it, 310 citations in OpenAlex.

  1. Guideline
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85 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Alastair J MossUniversity of Edinburgh/British Heart Foundation Centre for Cardiovascular Science, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB UK.
Michelle C WilliamsUniversity of Edinburgh/British Heart Foundation Centre for Cardiovascular Science, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB UK.
David E NewbyUniversity of Edinburgh/British Heart Foundation Centre for Cardiovascular Science, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB UK.
Edward D NicolDepartment of Cardiology, Royal Brompton Hospital and Harefield NHS Trust, Sydney Street, London, SW3 6NP UK.
University of Edinburgh · GBBritish Heart Foundation · GBRoyal Brompton Hospital · GB

Funding

Medical Research Council G0701127
6 · The paper itself

Abstract

purpose of reviewCost-effective care pathways are integral to delivering sustainable healthcare programmes. Due to the overestimation of coronary artery disease using traditional risk tables, non-invasive testing has been utilised to improve risk stratification and initiate appropriate management to reduce the dependence on invasive investigations. In line with recent technological improvements, cardiac CT is a modality that offers a detailed anatomical assessment of coronary artery disease comparable to invasive coronary angiography. RECENT

findingsThe recent publication of the National Institute for Health and Care Excellences (NICE) Clinical Guideline 95 update assesses the performance and cost utility of different non-invasive imaging strategies in patients presenting with suspected anginal chest pain. The low cost and high sensitivity of cardiac CT makes it the non-invasive test of choice in the evaluation of stable angina. This has now been ratified in national guidelines with NICE recommending cardiac CT as the first-line investigation for all patients presenting with chest pain due to suspected coronary artery disease. Additionally, randomised controlled trials have demonstrated that cardiac CT improves diagnostic certainty when incorporated into chest pain pathways. SUMMARY: NICE recommend cardiac CT as the first-line test for the evaluation of stable coronary artery disease in chest pain pathways.

Indexed as

AnginaChest painCoronary artery diseaseCoronary computed tomography angiography

Identifiers

PMID28446943
PMCPMC5368205
OpenAlexW2602944801

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.