ReviewOpen biology2017
Chemical roots of biological evolution: the origins of life as a process of development of autonomous functional systems.
Review in Open biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed.
- Sustained formation movement and destruction of coacervates in a waste-free system driven by electricity.Nature communications · 2026Article
- Non-enzymatic coupling of protometabolic reactions with a prebiotic redox cofactor.Nature communications · 2026Article
- Stimuli-Responsive Chemical Systems That Mimic Biological Dynamics.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Review
- Chemical arsenal for helicase Hunters: Striking the toughest targets in antiviral research.Antiviral research · 2025Article
- Darwinian Evolution of Self-Replicating DNA in a Synthetic Protocell.Nature communications · 2024Article
- Protocellular Heme and Iron-Sulfur Clusters.Accounts of chemical research · 2024Review
- Article
- Evidence of Heritability in Prebiotically Realistic Membrane-Bound Systems.Life (Basel, Switzerland) · 2024Article
- Life's building blocks: the modular path to multiscale complexity.Frontiers in systems biology · 2024Article
- Did organs precede organisms in the origin of life?microLife · 2024Article
- Integrating Multicellular Systems: Physiological Control and Degrees of Biological Individuality.Acta biotheoretica · 2023Article
- On the Emergence of Autonomous Chemical Systems through Dissipation Kinetics.Life (Basel, Switzerland) · 2023Article
- The protometabolic nature of prebiotic chemistry.Chemical Society reviews · 2023Review
- On the Chemical Origin of Biological Cognition.Life (Basel, Switzerland) · 2022Article
- Novel Apparatuses for Incorporating Natural Selection Processes into Origins-of-Life Experiments to Produce Adaptively Evolving Chemical Ecosystems.Life (Basel, Switzerland) · 2022Article
- Collective adaptability in a replication network of minimal nucleobase sequences.Chemical science · 2022Article
- The 'Is' and the 'Ought' of the Animal Organism: Hegel's Account of Biological Normativity.History and philosophy of the life sciences · 2022Article
- The scientific principles and technological determinants of haemodialysis membranes.Clinical kidney journal · 2021Review
- How Was Nature Able to Discover Its Own Laws-Twice?Life (Basel, Switzerland) · 2021Review
- Discovery in space of ethanolamine, the simplest phospholipid head group.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, an extension of the Darwinian framework is being considered for the study of prebiotic chemical evolution, shifting the attention from homogeneous populations of naked molecular species to populations of heterogeneous, compartmentalized and functionally integrated assemblies of molecules. Several implications of this shift of perspective are analysed in this critical review, both in terms of the individual units, which require an adequate characterization as self-maintaining systems with an internal organization, and also in relation to their collective and long-term evolutionary dynamics, based on competition, collaboration and selection processes among those complex individuals. On these lines, a concrete proposal for the set of molecular control mechanisms that must be coupled to bring about autonomous functional systems, at the interface between chemistry and biology, is provided.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.