ArticleThe Journal of nutrition2017
Dietary Methionine Restriction Regulates Liver Protein Synthesis and Gene Expression Independently of Eukaryotic Initiation Factor 2 Phosphorylation in Mice.
Erratum issuedOpen access · bronzeAbstract read
In one paragraph
Article in The Journal of nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 36 papers.
0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 50 citations in OpenAlex.
- Eight-week dietary methionine restriction does not impair resistance exercise-induced mTORC1 signalling activation in rats.Biochemistry and biophysics reports · 2026Article
- Dietary methionine depletion and hydrogen sulfide-producing genes in perivascular adipose tissue of male Wistar rats.Physiological reports · 2025Article
- Beyond Protein Building Blocks: A Review of Biological Roles and Therapeutic Potential of Free Amino Acids.International journal of molecular sciences · 2025Review
- Targeting macro- and micro-nutrient regulation of HNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Review
- Tissue-specific molecular regulation of aging mechanisms with methionine restriction in mice and the potential role of methionine sulfoxide reductase.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- GCN2 drives diurnal patterns in the hepatic integrated stress response and maintains circadian rhythms in whole body metabolism during amino acid insufficiency.American journal of physiology. Endocrinology and metabolism · 2024Article
- Computational modeling of the synergistic role of GCN2 and the HPA axis in regulating the integrated stress response in the central circadian timing system.Physiological genomics · 2024Article
- Rescue of Methionine Dependence by Cobalamin in a Human Colorectal Cancer Cell Line.Nutrients · 2024Article
- Physical activity of mice on dietary sulfur amino acid restriction is influenced by age of diet initiation and biological sex.Scientific reports · 2023Article
- GCN2 is required to maintain core body temperature in mice during acute cold.American journal of physiology. Endocrinology and metabolism · 2023Article
- Kinetic proteomics identifies targeted changes in liver metabolism and the ribo-interactome by dietary sulfur amino acid restriction.GeroScience · 2023Article
- Artesunate targets cellular metabolism to regulate the Th17/Treg cell balance.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023Review
- The integrated stress response protects against ER stress but is not required for altered translation and lifespan from dietary restriction inFrontiers in cell and developmental biology · 2023Article
- Cysteine restriction-specific effects of sulfur amino acid restriction on lipid metabolism.Aging cell · 2022Article
- The Origins, Evolution, and Future of Dietary Methionine Restriction.Annual review of nutrition · 2022Review
- Activation and execution of the hepatic integrated stress response by dietary essential amino acid deprivation is amino acid specific.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022Article
- Metabolic benefits of methionine restriction in adult mice do not require functional methionine sulfoxide reductase A (MsrA).Scientific reports · 2022Article
- Targeting the methionine addiction of cancer.American journal of cancer research · 2022Review
- Rates of protein synthesis are maintained in brain but reduced in skeletal muscle during dietary sulfur amino acid restriction.Frontiers in aging · 2022Article
- Methionine restriction exposes a targetable redox vulnerability of triple-negative breast cancer cells by inducing thioredoxin reductase.Breast cancer research and treatment · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors at 5 institutions in 2 countries.
Ashley P PettitDepartment of Nutritional Sciences, Rutgers University, New Brunswick, NJ.ORCID 0000-0001-5536-3245
William O JonssonDepartment of Nutritional Sciences, Rutgers University, New Brunswick, NJ.
Albert R BargoudDepartment of Nutritional Sciences, Rutgers University, New Brunswick, NJ.
Emily T MirekDepartment of Nutritional Sciences, Rutgers University, New Brunswick, NJ.
Frederick F PeelorDepartment of Health and Exercise Science, Colorado State University, Fort Collins, CO.
Yongping WangDepartment of Nutritional Sciences, Rutgers University, New Brunswick, NJ.
Thomas W GettysLaboratory of Nutrient Sensing and Adipocyte Signaling, Pennington Biomedical Research Center, Baton Rouge, LA.ORCID 0000-0001-7125-7995
Scot R KimballDepartment of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey PA; and.
Benjamin F MillerDepartment of Health and Exercise Science, Colorado State University, Fort Collins, CO.
Karyn L HamiltonDepartment of Health and Exercise Science, Colorado State University, Fort Collins, CO.
Ronald C WekDepartment of Biochemistry of Molecular Biology, Indiana University School of Medicine, Indianapolis, IN.
Tracy G AnthonyDepartment of Nutritional Sciences, Rutgers University, New Brunswick, NJ; tracy.anthony@rutgers.edu.ORCID 0000-0002-8586-5884
Rutgers, The State University of New Jersey · USColorado State University · USIndiana University School of MedicinePennington Biomedical Research Center · USPennsylvania State University · US
Funding
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6MIRACDA at Rutgers: INSPIRE Postdoctoral Training ProgramK12GM093854 · NIGMS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Detlev Boison, Gary A. Brewer · 2010 to 2026
$14.7MTHE ROLE OF PROTEIN MALNUTRITION ON CIRCADIAN PHYSIOLOGY OF C57BL/6J MOUSE DAMSP20RR021945 · NCRR · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI GETTYS, THOMAS W · 2006 to 2011
$9.5MMentoring Obesity and Diabetes Research in LouisianaP20GM103528 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI GETTYS, THOMAS W · 2012 to 2015
$8.8MREGULATION OF LIVER GROWTH AND FUNCTIONR01DK013499 · NIDDK · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KIMBALL, SCOT R · 1995 to 2018
$8.0MREGULATION OF SKELETAL MUSCLE METABOLISMR01DK015658 · NIDDK · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KIMBALL, SCOT R · 1986 to 2021
$7.4MTransgenics CoreP30GM118430 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI GETTYS, THOMAS W · 2016 to 2020
$5.8MHomeostatic Responses to Amino Acid InsufficiencyR01DK109714 · NIDDK · RUTGERS, THE STATE UNIV OF N.J. · PI ANTHONY, TRACY G., WEK, RONALD C · 2016 to 2024
$5.4MMECHANISMS OF METABOLIC REGULATION BY DIETARY METHIONINE RESTRICTIONR01DK096311 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI GETTYS, THOMAS W · 2012 to 2020
$2.7MMolecular Mechanisms of Adverse Metabolic Events by Asparaginase.R01HD070487 · NICHD · RUTGERS, THE STATE UNIV OF N.J. · PI ANTHONY, TRACY G. · 2011 to 2015
$1.9MTranslational mechanisms of mitochondrial protein synthesisR01AG042569 · NIA · COLORADO STATE UNIVERSITY · PI HAMILTON, KARYN L, MILLER, BENJAMIN FRANCIS · 2013 to 2017
$1.5MNCRR NIH HHS P20 RR021945NIA NIH HHS R01 AG042569NICHD NIH HHS R01 HD070487NIDDK NIH HHS P30 DK048520NIDDK NIH HHS R01 DK013499NIDDK NIH HHS R01 DK015658NIDDK NIH HHS R01 DK096311NIDDK NIH HHS R01 DK109714NIGMS NIH HHS K12 GM093854NIGMS NIH HHS P20 GM103528NIGMS NIH HHS P30 GM118430
Abstract
PubMed holds no abstract for this paper.
Indexed as
DietProtein BiosynthesisStress, PhysiologicalActivating Transcription Factor 4Adipose TissueAnimalsBody CompositioneIF-2 KinaseEndoplasmic ReticulumEukaryotic Initiation Factor-2FemaleGene ExpressionGene Expression RegulationLiverMaleMetabolic DiseasesActivating Transcription Factor 4Atf4 protein, mouseEif2ak4 protein, mouseeIF-2 KinaseEukaryotic Initiation Factor-2MethionineProtein Serine-Threonine KinasesRNA, MessengerATF4eIF2BGCN2integrated stress responsePERK
Identifiers
What OpenQuestion holds
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.