Evidence map›Paper›PMID 28446612›Full record

ArticleThe Journal of biological chemistry2017

CDK4 protein is degraded by anaphase-promoting complex/cyclosome in mitosis and reaccumulates in early G

Huabo Chen, Xiaowei Xu, Guopeng Wang, Boyan Zhang, Gang Wang, Guangwei Xin, Junjun Liu, Qing Jiang, Hongyin Zhang, Chuanmao Zhang

Open access · hybridAbstract readComparative Study
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. CDKN2A/B Homozygous Deletion Sensitizes IDH-Mutant Glioma to CDK4/6 Inhibition.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Cyclin D1 Stability Is Partly Controlled byFrontiers in endocrinology · 2019
    Article
  14. Review
  15. Article
  16. Copper Chaperone Atox1 Interacts with Cell Cycle Proteins.Computational and structural biotechnology journal · 2018
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Huabo ChenFrom the Ministry of Education Key Laboratory of Cell Proliferation and Differentiation and the State Key Laboratory of Membrane Biology, College of Life Sciences, Peking University, Beijing 100871, China.
Xiaowei XuFrom the Ministry of Education Key Laboratory of Cell Proliferation and Differentiation and the State Key Laboratory of Membrane Biology, College of Life Sciences, Peking University, Beijing 100871, China.
Guopeng WangFrom the Ministry of Education Key Laboratory of Cell Proliferation and Differentiation and the State Key Laboratory of Membrane Biology, College of Life Sciences, Peking University, Beijing 100871, China.
Boyan ZhangFrom the Ministry of Education Key Laboratory of Cell Proliferation and Differentiation and the State Key Laboratory of Membrane Biology, College of Life Sciences, Peking University, Beijing 100871, China.
Gang WangFrom the Ministry of Education Key Laboratory of Cell Proliferation and Differentiation and the State Key Laboratory of Membrane Biology, College of Life Sciences, Peking University, Beijing 100871, China.
Guangwei XinFrom the Ministry of Education Key Laboratory of Cell Proliferation and Differentiation and the State Key Laboratory of Membrane Biology, College of Life Sciences, Peking University, Beijing 100871, China.
Junjun Liuthe Department of Biological Sciences, California State Polytechnic University, Pomona, California 91768.
Qing JiangFrom the Ministry of Education Key Laboratory of Cell Proliferation and Differentiation and the State Key Laboratory of Membrane Biology, College of Life Sciences, Peking University, Beijing 100871, China, jiangqing@pku.edu.cn.
Hongyin Zhangthe Cancer Research Center, Peking University Hospital, Peking University, Beijing 100871, China, and.
Chuanmao ZhangFrom the Ministry of Education Key Laboratory of Cell Proliferation and Differentiation and the State Key Laboratory of Membrane Biology, College of Life Sciences, Peking University, Beijing 100871, China, zhangcm@pku.edu.cn.
Peking University · CNState Key Laboratory of Membrane BiologyCalifornia State Polytechnic University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CDK4 regulates G

Indexed as

G1 PhaseMitosisActive Transport, Cell NucleusAnaphase-Promoting Complex-CyclosomeAnimalsCell LineCyclin D1Cyclin-Dependent Kinase 4Enzyme InductionEnzyme StabilityGreen Fluorescent ProteinsHeLa CellsHumansMiceNeoplasm ProteinsNuclear Localization SignalsAnaphase-Promoting Complex-CyclosomeCCND1 protein, humanCDK4 protein, humanCyclin D1Cyclin-Dependent Kinase 4Green Fluorescent ProteinsNeoplasm ProteinsNuclear Localization SignalsPeptide FragmentsRecombinant Fusion Proteinscell cyclecyclin D1cyclin-dependent kinase (CDK)protein degradationretinoblastoma protein (pRb, RB)

Identifiers

PMID28446612
PMCPMC5473219
OpenAlexW2609816058

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.