Evidence map›Paper›PMID 28446604›Full record

ArticleThe Journal of biological chemistry2017

Cell cycle-dependent regulation of Greatwall kinase by protein phosphatase 1 and regulatory subunit 3B.

Dapeng Ren, Laura A Fisher, Jing Zhao, Ling Wang, Byron C Williams, Michael L Goldberg, Aimin Peng

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. The ATM-E6AP-MASTL axis mediates DNA damage checkpoint recovery.bioRxiv : the preprint server for biology · 2023
    Article
  4. Review
  5. Dephosphorylation in nuclear reassembly after mitosis.Frontiers in cell and developmental biology · 2022
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Protein phosphatases in the regulation of mitosis.The Journal of cell biology · 2019
    Review
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Dapeng RenFrom the Department of Oral Biology, College of Dentistry, University of Nebraska Medical Center, Lincoln, Nebraska 68583 and.
Laura A FisherFrom the Department of Oral Biology, College of Dentistry, University of Nebraska Medical Center, Lincoln, Nebraska 68583 and.
Jing ZhaoFrom the Department of Oral Biology, College of Dentistry, University of Nebraska Medical Center, Lincoln, Nebraska 68583 and.
Ling WangFrom the Department of Oral Biology, College of Dentistry, University of Nebraska Medical Center, Lincoln, Nebraska 68583 and.
Byron C Williamsthe Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853.
Michael L Goldbergthe Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853.
Aimin PengFrom the Department of Oral Biology, College of Dentistry, University of Nebraska Medical Center, Lincoln, Nebraska 68583 and Aimin.Peng@UNMC.edu.
University of Nebraska Medical Center · USCornell University · US

Funding

Greatwall Kinase and the Mitotic Control of Phosphatase ActivityR01GM048430 · NIGMS · CORNELL UNIVERSITY ITHACA · PI GOLDBERG, MICHAEL L · 1992 to 2017
$6.6M
Research Pilot Project ProgramP30GM106397 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI JOHNSON, KEITH R · 2013 to 2017
$4.9M
Nebraska Center for Cellular SignalingP20GM103489 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI JOHNSON, KEITH R · 2012 to 2012
$2.0M
DNA Damage Checkpoint Recovery and CancerR01CA172574 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI PENG, AIMIN · 2013 to 2017
$1.6M
NCI NIH HHS R01 CA172574NIGMS NIH HHS P20 GM103489NIGMS NIH HHS P30 GM106397NIGMS NIH HHS R01 GM048430
6 · The paper itself

Abstract

Greatwall (Gwl) kinase plays an essential role in the regulation of mitotic entry and progression. Mitotic activation of Gwl requires both cyclin-dependent kinase 1 (CDK1)-dependent phosphorylation and its autophosphorylation at an evolutionarily conserved serine residue near the carboxyl terminus (Ser-883 in

Indexed as

Cell CycleProtein Processing, Post-TranslationalAmino Acid SubstitutionAnimalsCell DivisionCyclin-Dependent KinasesEnzyme ActivationHeLa CellsHumansIntracellular Signaling Peptides and ProteinsMitosisMutationOocytesPhosphorylationProtein Phosphatase 1Protein Serine-Threonine KinasesCyclin-Dependent KinasesIntracellular Signaling Peptides and ProteinsMASTL protein, XenopusProtein Phosphatase 1Protein Serine-Threonine KinasesProtein SubunitsRecombinant Fusion ProteinsRecombinant ProteinsRepressor ProteinsSerineXenopus Proteinscell cyclemitosisphosphatasephosphoprotein phosphatase 1 (PP1)Xenopus

Identifiers

PMID28446604
PMCPMC5473210
OpenAlexW2607778805

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.