Evidence map›Paper›PMID 28446592›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2017

Débora M Cerqueira, Andrew J Bodnar, Yu Leng Phua, Rachel Freer, Shelby L Hemker, Loren D Walensky, Neil A Hukriede, Jacqueline Ho

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Role of microRNAs in Obesity-Related Kidney Disease.International journal of molecular sciences · 2021
    Review
  6. Article
  7. Epigenetic regulation of kidney progenitor cells.Stem cells translational medicine · 2020
    Review
  8. Deletion of hypoxia-responsive microRNA-210 results in a sex-specific decrease in nephron number.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  9. In utero exposure to maternal diabetes impairs nephron progenitor differentiation.American journal of physiology. Renal physiology · 2019
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Débora M CerqueiraDivision of Nephrology, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Andrew J BodnarDivision of Nephrology, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Yu Leng PhuaDivision of Nephrology, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Rachel FreerDivision of Nephrology, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Shelby L HemkerDivision of Nephrology, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Loren D WalenskyDepartment of Pediatric Oncology and the Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Neil A HukriedeDepartment of Developmental Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Jacqueline HoDivision of Nephrology, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; jacqueline.ho2@chp.edu.
University of Pittsburgh · USBoston Children's Hospital · US

Funding

Single Nephron and MetabolomicsP30DK079307 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CARATTINO, MARCELO DANIEL · 2008 to 2022
$13.4M
Regulation of Renal Progenitor Cells in Regenerating KidneysR01DK069403 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HUKRIEDE, NEIL A · 2006 to 2020
$4.8M
Renal and Epithelial Biology Training ProgramT32DK061296 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2002 to 2022
$3.1M
Utilizing Small Molecule Screens to Delineate Embryonic Signaling MechanismsR01HD053287 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HUKRIEDE, NEIL A, TSANG, MICHAEL WAIKOK · 2007 to 2016
$3.1M
The Role of miR-17~92 in Nephron ProgenitorsR01DK103776 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HO, JACQUELINE · 2014 to 2018
$1.7M
MicroRNAs in Kidney Progenitor Cells.R00DK087922 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HO, JACQUELINE · 2012 to 2014
$722k
MicroRNAs in kidney progenitor cells.K99DK087922 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HO, JACQUELINE · 2010 to 2011
$216k
NICHD NIH HHS R01 HD053287NIDDK NIH HHS K99 DK087922NIDDK NIH HHS P30 DK079307NIDDK NIH HHS R00 DK087922NIDDK NIH HHS R01 DK069403NIDDK NIH HHS R01 DK103776NIDDK NIH HHS T32 DK061296
6 · The paper itself

Abstract

Low nephron endowment at birth has been associated with an increased risk for developing hypertension and chronic kidney disease. We demonstrated in an earlier study that conditional deletion of the microRNA (miRNA)-processing enzyme Dicer from nephron progenitors results in premature depletion of the progenitors and increased expression of the proapoptotic protein Bim (also known as Bcl-2L11). In this study, we generated a compound mouse model with conditional deletion of both

Indexed as

AnimalsApoptosisBcl-2-Like Protein 11DEAD-box RNA HelicasesEmbryo, NonmammalianGene DeletionGene DosageGene Expression Regulation, DevelopmentalHEK293 CellsHumansKidneyMiceMice, TransgenicMicroRNAsNephronsRibonuclease IIIBcl2l11 protein, mouseBcl-2-Like Protein 11DEAD-box RNA HelicasesDicer1 protein, mouseMicroRNAsRibonuclease IIIapoptosisBcl-2L11Dicermetanephrosnephrogenesis

Identifiers

PMID28446592
PMCPMC5503708
OpenAlexW2608959282

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.