Evidence map›Paper›PMID 28446351›Full record

ArticleDeutsches Arzteblatt international2017

Deep Vein Thrombosis of the Upper Extremity.

Jan Heil, Wolfgang Miesbach, Thomas Vogl, Wolf O Bechstein, Alexander Reinisch

Abstract read
In one paragraph

Article in Deutsches Arzteblatt international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  9. Article
  10. A Comprehensive Review of Catheter-Related Thrombosis.Journal of clinical medicine · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Upper Arm Deep Vein Thrombosis in a Patient with Active Lupus.European journal of case reports in internal medicine · 2024
    Article
  15. Article
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Jan HeilDepartment of General and Visceral Surgery, University Hospital Frankfurt, Frankfurt am Main; Hemostasiology, Department of Medicine II, University Hospital Frankfurt, Frankfurt am Main; Institute of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt am Main.
Wolfgang Miesbach
Thomas Vogl
Wolf O Bechstein
Alexander Reinisch

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeep venous thrombosis (DVT) arises with an incidence of about 1 per 1000 persons per year; 4-10% of all DVTs are located in an upper extremity (DVT-UE). DVT-UE can lead to complications such as post-thrombotic syndrome and pulmonary embolism and carries a high mortality.

methodsThis review is based on pertinent literature, published from January 1980 to May 2016, that was retrieved by a systematic search, employing the PRISMA criteria, carried out in four databases: PubMed (n = 749), EMBASE (n = 789), SciSearch (n = 0), and the Cochrane Library (n = 12). Guidelines were included in the search.

resultsDVT-UE arises mainly in patients with severe underlying diseases, especially cancer (odds ratio [OR] 18.1; 95% confidence interval [9.4; 35.1]). The insertion of venous catheters-particularly central venous catheters-also elevates the risk of DVT-UE. Its clinical manifestations are nonspecific. Diagnostic algorithms are of little use, but ultrasonography is very helpful in diagnosis. DVT-UE is treated by anticoagulation, with heparin at first and then with oral anticoagulants. Direct oral anticoagulants are now being increasingly used. The thrombus is often not totally eradicated. Anticoagulation is generally continued as maintenance treatment for 3-6 months. Interventional techniques can be used for special indications. Patients with DVT-UE have a high mortality, though they often die of their underlying diseases rather than of the DVT-UE or its complications.

conclusionDVT of the upper extremity is becoming increasingly common, though still much less common than DVT of the lower extremity. The treatment of choice is anticoagulation, which is given analogously to that given for DVT of the lower extremity.

Indexed as

Venous ThrombosisAnticoagulantsArmHumansIncidenceMalePulmonary EmbolismUltrasonographyAnticoagulants

Identifiers

PMID28446351
PMCPMC5415909

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.