Evidence map›Paper›PMID 28446193›Full record

ArticleActa veterinaria Scandinavica2017

Liver morphometrics and metabolic blood profile across divergent phenotypes for feed efficiency in the bovine.

Yuri Regis Montanholi, Livia Sadocco Haas, Kendall Carl Swanson, Brenda Lynn Coomber, Shigeto Yamashiro, Stephen Paul Miller

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta veterinaria Scandinavica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Yuri Regis MontanholiDepartment of Animal Science and Aquaculture, Faculty of Agriculture, Dalhousie University, 58 River Road, Bible Hill, Truro, NS, B2N 5E3, Canada. Yuri.R.Montanholi@gmail.com.
Livia Sadocco HaasFaculdade de Medicina Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, 91540-000, Brazil.
Kendall Carl SwansonDepartment of Animal Sciences, North Dakota State University, Fargo, ND, 58102, USA.
Brenda Lynn CoomberDepartment of Biomedical Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada.
Shigeto YamashiroDepartment of Biomedical Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada.
Stephen Paul MillerDepartment of Animal Biosciences, University of Guelph, Guelph, ON, N1G 2W1, Canada.
University of Guelph · CADalhousie University · CANorth Dakota State University · USUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFeed costs are a major expense in the production of beef cattle. Individual variation in the efficiency of feed utilization may be evident through feed efficiency-related phenotypes such as those related to major energetic sinks. Our objectives were to assess the relationships between feed efficiency with liver morphometry and metabolic blood profile in feedlot beef cattle.

methodsTwo populations (A = 112 and B = 45) of steers were tested for feed efficiency. Blood from the 12 most (efficient) and 12 least feed inefficient (inefficient) steers from population A was sampled hourly over the circadian period. Blood plasma samples were submitted for analysis on albumin, aspartate aminotransferase, γ-glutamyl transpeptidase urea, cholesterol, creatinine, alkaline phosphatase, creatine kinase, lipase, carbon dioxide, β-hydroxybutyrate, acetate and bile acids. Liver tissue was also harvested from 24 steers that were blood sampled from population A and the 10 steers with divergent feed efficiency in each tail of population B was sampled for microscopy at slaughter. Photomicroscopy images were taken using the portal triad and central vein as landmarks. Histological quantifications included cross-sectional hepatocyte perimeter and area, hepatocyte nuclear area and nuclei area as proportion of the hepatocyte area. The least square means comparison between efficient and inefficient steers for productive performance and liver morphometry and for blood analytes data were analyzed using general linear model and mixed model procedures of SAS, respectively.

resultsNo differences were observed for liver weight; however, efficient steers had larger hepatocyte (i.e. hepatocyte area at the porta triad 323.31 vs. 286.37 µm

conclusionsImproved feed efficiency is associated with increased metabolism by the liver (enlarged hepatocytes and no difference on organ size), muscle (higher creatinine) and whole body (higher carbon dioxide); additionally, efficient steers had reduced bloodstream pools of albumin and cholesterol. These metabolic discrepancies between feed efficient and inefficient cattle may be determinants of productive performance.

Indexed as

Animal FeedAnimalsBody CompositionCarbon DioxideCattleCholesterolCircadian RhythmCreatinineEatingLiverMaleOrgan SizeSerum AlbuminSerum Albumin, HumanWeight Gainalbumin AmsterdamCarbon DioxideCholesterolCreatinineSerum AlbuminSerum Albumin, HumanAlbuminCarbon dioxideCholesterolCreatinineEnergy metabolismHepatocyte dimensionsHistomorphometryLiver sizeMetabolic rateResidual feed intake

Identifiers

PMID28446193
PMCPMC5405500
OpenAlexW4243124150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.