ArticleBMC nephrology2017
IgG4-related membranous glomerulonephritis and generalized lymphadenopathy without pancreatitis: a case report.
Article in BMC nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Remission Induction of IgG4-related Membranous Nephropathy with Multitarget Therapy.Internal medicine (Tokyo, Japan) · 2023Article
- Folic acid-induced animal model of kidney disease.Animal models and experimental medicine · 2021Review
- Low-density lipoprotein apheresis for PLA2R-related membranous glomerulonephritis accompanied by IgG4-related tubulointerstitial nephritis.CEN case reports · 2020Article
- Identification of biomarkers and drug repurposing candidates based on an immune-, inflammation- and membranous glomerulonephritis-associated triplets network for membranous glomerulonephritis.BMC medical genomics · 2020Article
- Perirenal capsule and scrotal involvement in immunoglobulin G4-related kidney disease: case-based review.Rheumatology international · 2018Review
- IgG4-Related Pancreatitis and Immune Thrombocytopenia: A Case Report and Literature Review.Cureus · 2017Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundIgG4-related disease is a recently described pathologic entity. This is the case of a patient with nephrotic syndrome and lymphadenopathy due to IgG4-related disease. Such a kidney involvement is quite peculiar and has only been described a few times recently. Renal biopsy showed a glomerular involvement with membranous glomerulonephritis in association with a tubulo-interstitial nephropathy. Moreover, the patient was not suffering from pancreatitis. CASE PRESENTATION: The patient is a middle-aged man of Moroccan origin. He has developed recurrent episodes of diffuse lymphadenopathies, renal failure and nephrotic syndrome. Renal biopsies showed membranous glomerulonephritis. DISCUSSION AND
conclusionThe diagnostic approach of this atypical presentation is discussed in this case report as well as diagnostic criteria, therapeutic strategies, biomarkers and pathophysiology of IgG4-related disease. IgG4-related membranous glomerulonephritis is a well-established cause of membranous glomerulonephritis. It must be sought after in every patient with a previous diagnosis of IgG4-related disease and in every patient with this histological finding on renal biopsy. Corticoids are still the first-line treatment of IgG4-related disease. New therapeutic strategies are needed to avoid glucocorticoids long term side-effects. Interestingly, the patient was prescribed cyclophosphamide in addition to glucocorticoids for an immune thrombocytopenia. This treatment had a very good impact on his IgG4-related disease.
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