SynthesisOncotarget2017
Palliative radiotherapy for gastric cancer: a systematic review and meta-analysis.
Synthesis in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Gastric cancer radiation therapy: a bibliometric analysis of the scientific literature.Frontiers in oncology · 2025Pooled it
- Effects of Aromatherapy on Physical and Mental Health of Cancer Patients Undergoing Radiotherapy and/or Chemotherapy: A Meta-Analysis.Chinese journal of integrative medicine · 2024Pooled it
- Palliative radiotherapy for gastric cancer: Is there a dose relationship between bleeding response and radiotherapy?Clinics (Sao Paulo, Brazil) · 2020Pooled it
- Palliative radiotherapy in symptomatic locally advanced gastric cancer: A phase II trial.Cancer medicine · 2019Trial
- Hemostatic single-fraction 8 Gy radiotherapy for tumor bleeding: a single-centre retrospective study.Japanese journal of radiology · 2026Article
- Radiotherapy as an antihemorrhagic approach in gastric cancer: the RANTIGA study.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026Article
- Stage-dependent survival in gastric cancer: a Danish nationwide cohort study.Langenbeck's archives of surgery · 2025Article
- Hemostatic palliative radiotherapy for gastric cancer: A literature review.Technical innovations & patient support in radiation oncology · 2024Review
- Gastric transcatheter chemoembolization combined with systemic chemotherapy vs. systemic chemotherapy alone for patients with advanced gastric cardiac cancer presenting with dysphagia: A case control study.Oncology letters · 2024Article
- Time to treatment disparities in gastric cancer patients in the United States of America: a comprehensive retrospective analysis.Frontiers in oncology · 2024Article
- Emergency exploratory laparotomy and radical gastrectomy in patients with gastric cancer combined with acute upper gastrointestinal bleeding.World journal of gastrointestinal surgery · 2023Article
- Challenges in managing upper gastrointestinal bleeding secondary to primary squamous cell carcinoma of the pancreas: a case report and literature review.Surgical case reports · 2023Article
- Palliative Radiotherapy for Esophageal and Gastric Cancer: Population-Based Patterns of Utilization and Outcomes in Ontario, Canada.Journal of palliative care · 2023Article
- Clinical outcomes of palliative treatment for gastric bleeding from incurable gastric cancer.Surgery today · 2023Article
- Palliative radiation therapy for bleeding from gastric cancer: A case series of seven patients.Clinical case reports · 2023Article
- Application and progress of palliative therapy in advanced gastric carcinomas.Frontiers in oncology · 2023Review
- Optimizing the Continuum of Care in Gastric Cancer.OncoTargets and therapy · 2023Review
- Article
- Identification of a chemotherapy-associated gene signature for a risk model of prognosis in gastric adenocarcinoma through bioinformatics analysis.Journal of gastrointestinal oncology · 2022Article
- Bayesian Network Analysis for Prediction of Unplanned Hospital Readmissions of Cancer Patients with Breakthrough Cancer Pain and Complex Care Needs.Healthcare (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background/purposeTo review the efficacy and toxicity of palliative radiotherapy (RT) for symptomatic locally advanced gastric cancer (GC) and to determine the optimal RT schedule for symptom palliation.
methodsWe searched MEDLINE and CENTRAL for eligible studies published from 1995 to 2015. Outcomes of interest were relief of bleeding, pain and obstruction.
resultsSeven non-comparative observational studies were included. There were large variations in RT dose and fractionation. The pooled overall response rates for bleeding, pain and obstruction symptoms were 74%, 67% and 68% respectively. There was no difference in response rate of bleeding between regimens with high biological equivalent dose (BED) of ≥ 39Gy versus regimens with low BED<39Gy regimens (p value =0.39). Grade 3 to 4 toxicities occurred in up to 15% of patients for patients treated with RT alone and up to 25% of patients treated with chemoradiotherapy. Health-related quality of life (HRQL) outcomes were not reported.
conclusionMore than two-thirds of patients receiving RT would have a clinical benefit. Low BED regimens appear to be adequate for symptom palliation. Toxicity rates appear acceptable for patients treated with RT alone. The optimal dose fractionation regimen for symptom palliation remains unclear. Prospective studies to determine the effects of palliative gastric RT on HRQL outcomes are warranted.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.