Evidence map›Paper›PMID 28445802›Full record

ReviewCurrent opinion in genetics & development2017

NMNAT: It's an NAD

Jennifer M Brazill, Chong Li, Yi Zhu, R Grace Zhai

Abstract readReview
In one paragraph

Review in Current opinion in genetics & development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 74 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Protein Acetylation and NAD+ Homeostasis in Aging Muscle.Advances in experimental medicine and biology · 2025
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. NADSub-cellular biochemistry · 2024
    Review
  17. Review
  18. Article
  19. Review
  20. Pathogenesis of Dementia.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jennifer M BrazillDepartment of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL 33136, United States.
Chong LiDepartment of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL 33136, United States.
Yi ZhuDepartment of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL 33136, United States.
R Grace ZhaiDepartment of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL 33136, United States. Electronic address: gzhai@miami.edu.
University of Miami · US

Funding

Mechanisms of Neuronal Maintenance and Protection.R01NS064269 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ZHAI, RONG GRACE · 2009 to 2013
$1.6M
Mechanisms of Neuronal Maintenance and ProtectionR56NS064269 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ZHAI, RONG GRACE · 2015 to 2015
$336k
NINDS NIH HHS R01 NS064269NINDS NIH HHS R56 NS064269
6 · The paper itself

Abstract

Nicotinamide mononucleotide adenylyl transferases (NMNATs) are a family of highly conserved proteins indispensable for cellular homeostasis. NMNATs are classically known for their enzymatic function of catalyzing NAD

Indexed as

Amide SynthasesHumansMolecular ChaperonesNADNeurodegenerative DiseasesNeuronsNicotinamide-Nucleotide AdenylyltransferaseAmide SynthasesMolecular ChaperonesNADNAD+ synthaseNicotinamide-Nucleotide Adenylyltransferase

Identifiers

PMID28445802
PMCPMC5515290
OpenAlexW2605677673

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.