Evidence map›Paper›PMID 28445618›Full record

ArticleJournal of diabetes investigation2018

Ficolin-3/adiponectin ratio for the prediction of gestational diabetes mellitus in pregnant women.

Xiao-Song Yuan, Hui Shi, Hui-Yan Wang, Bin Yu, Jian Jiang

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes investigation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  4. Observational
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  13. New Insights into Adipokines in Gestational Diabetes Mellitus.International journal of molecular sciences · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Xiao-Song YuanDepartment of Laboratory Medicine, Changzhou Maternity and Child Health Hospital Affiliated to Nanjing Medical University, Changzhou, China.ORCID http://orcid.org/0000-0003-2629-2243
Hui ShiDepartment of Laboratory Medicine, Jiangsu Institute of Planned Parenthood Research, Nanjing, China.
Hui-Yan WangDepartment of Obstetrics and Gynecology, Changzhou Maternity and Child Health Hospital Affiliated to Nanjing Medical University, Changzhou, China.
Bin YuDepartment of Laboratory Medicine, Changzhou Maternity and Child Health Hospital Affiliated to Nanjing Medical University, Changzhou, China.
Jian JiangDepartment of Obstetrics and Gynecology, Changzhou Maternity and Child Health Hospital Affiliated to Nanjing Medical University, Changzhou, China.
Nanjing Maternity and Child Health Care Hospital · CNPlanned Parenthood · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIMS/

introductionTo establish that the ficolin-3/adiponectin ratio is a predictor for gestational diabetes mellitus (GDM) and is eligible for screening tests for GDM. MATERIALS AND

methodsA prospective cohort study of 86 pregnant women who developed GDM and 273 normal glucose tolerance participants was carried out. Maternal serum ficolin-3, adiponectin levels were investigated at 16-18 weeks of gestation using enzyme-linked immunosorbent assay.

resultsCompared with the normal glucose tolerance group, the GDM group showed significantly higher levels of ficolin-3 and the ratio of ficolin-3/adiponectin; and decreased levels of adiponectin between 16-18 weeks of gestation (P < 0.05 or P < 0.01). The cut-off values for the ratio of ficolin-3/adiponectin (≥1.06; sensitivity 90.9%, specificity 96.5%) to discriminate the pregnant women who developed GDM from the non-diabetic cases were identified using receiver operating characteristic analysis. Using binary logistic regression analysis, ficolin-3, retinol-binding protein-4 and adiponectin, but not C-reactive protein, triglyceride and free fatty acids were shown as predictive factors for GDM.

conclusionsThe ratio of ficolin-3/adiponectin at 16-18 weeks of gestation was changed in pregnant women who subsequently developed GDM, and might provide effective early predicting and screening for GDM.

Indexed as

AdiponectinAdultBiomarkersDiabetes, GestationalFemaleGlycoproteinsHumansLectinsPregnancyProspective StudiesSensitivity and SpecificityAdiponectinADIPOQ protein, humanBiomarkersFCN3 protein, humanGlycoproteinsLectinsBiological markerFicolin-3Gestational diabetes mellitus

Identifiers

PMID28445618
PMCPMC5835472
OpenAlexW2609275209

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.