Evidence map›Paper›PMID 28445416›Full record

ArticleViruses2017

Structure-Function Model for Kissing Loop Interactions That Initiate Dimerization of Ty1 RNA.

Eric R Gamache, Jung H Doh, Justin Ritz, Alain Laederach, Stanislav Bellaousov, David H Mathews, M Joan Curcio

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. An interchangeable prion-like domain is required for Ty1 retrotransposition.Proceedings of the National Academy of Sciences of the United States of America · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Eric R GamacheLaboratory of Molecular Genetics, Wadsworth Center, New York State Department of Health, Albany, NY 12201, USA. egamache@iu.edu.
Jung H DohLaboratory of Molecular Genetics, Wadsworth Center, New York State Department of Health, Albany, NY 12201, USA. junghdoh@gmail.com.
Justin RitzDepartment of Biology, University of North Carolina, Chapel Hill, NC 27599, USA. justin.ritz1@gmail.com.
Alain LaederachDepartment of Biology, University of North Carolina, Chapel Hill, NC 27599, USA. alain@unc.edu.
Stanislav BellaousovDepartment of Biochemistry and Biophysics and Center for RNA Biology, University of Rochester Medical Center, Rochester, NY 14642, USA. stasuofr@gmail.com.
David H MathewsDepartment of Biochemistry and Biophysics and Center for RNA Biology, University of Rochester Medical Center, Rochester, NY 14642, USA. David_Mathews@URMC.Rochester.edu.
M Joan CurcioLaboratory of Molecular Genetics, Wadsworth Center, New York State Department of Health, Albany, NY 12201, USA. joan.curcio@health.ny.gov.
New York State Department of Health · USUniversity of North Carolina at Chapel Hill · USUniversity of Rochester Medical Center · US

Funding

Non-coding RNA structure change in Chronic Obstructive Pulmonary DiseaseR01HL111527 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Alain T Laederach, Kevin M Weeks · 2012 to 2026
$6.6M
Supporting RNAstructure: Software for RNA AnalysisR01GM076485 · NIGMS · UNIVERSITY OF ROCHESTER · PI MATHEWS, DAVID H. · 2006 to 2021
$4.7M
REGULATION OF RETROTRANSPOSITION IN S. CEREVISIAER01GM052072 · NIGMS · WADSWORTH CENTER · PI CURCIO, M JOAN · 2000 to 2013
$3.3M
Structural and functional consequences of disease SNPs on the transcriptomeR01GM101237 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LAEDERACH, ALAIN T · 2012 to 2020
$2.5M
Predicting the causative SNPs in LD blocks by allele-specific structural analysisR01HG008133 · NHGRI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LAEDERACH, ALAIN T, WEEKS, KEVIN M · 2015 to 2017
$2.4M
ConProject-001R01GM126554 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI HEITSCH, CHRISTINE E · 2017 to 2021
$1.7M
Identifying Disease-Associated Mutations That Alter RNA StructureR21MH087336 · NIMH · WADSWORTH CENTER · PI CURCIO, M JOAN · 2009 to 2010
$471k
NHGRI NIH HHS R01 HG008133NHLBI NIH HHS R01 HL111527NIGMS NIH HHS R01 GM052072NIGMS NIH HHS R01 GM076485NIGMS NIH HHS R01 GM101237NIGMS NIH HHS R01 GM126554NIMH NIH HHS R21 MH087336
6 · The paper itself

Abstract

The genomic RNA of the retrotransposon Ty1 is packaged as a dimer into virus-like particles. The 5' terminus of Ty1 RNA harbors

Indexed as

RetroelementsDimerizationNucleic Acid ConformationNucleotide MotifsPeptide Chain Initiation, TranslationalRetroviridaeReverse TranscriptionRNARNA, ViralSaccharomyces cerevisiaeTranscription, GeneticRetroelementsRNARNA, Viralkissing looplong terminal repeat-retrotransposonpseudoknotRNA kissing complexRNA packagingRNA secondary structureSaccharomyces cerevisiaeSHAPE analysisTy1

Identifiers

PMID28445416
PMCPMC5454406
OpenAlexW2608102389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.