Evidence map›Paper›PMID 28445397›Full record

ReviewInternational journal of molecular sciences2017

Radiation and Thyroid Cancer.

Elisabetta Albi, Samuela Cataldi, Andrea Lazzarini, Michela Codini, Tommaso Beccari, Francesco Saverio Ambesi-Impiombato, Francesco Curcio

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 2 syntheses or guidelines pooled it, 129 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Elisabetta AlbiDepartment of Pharmaceutical Science, University of Perugia, 06123 Perugia, Italy. elisabetta.albi@unipg.it.
Samuela CataldiDepartment of Pharmaceutical Science, University of Perugia, 06123 Perugia, Italy. samuelacataldi@libero.it.
Andrea LazzariniResearch Center and Analysis Laboratory CRABiON, 06073 Perugia, Italy. andrylazza@gmail.it.
Michela CodiniDepartment of Pharmaceutical Science, University of Perugia, 06123 Perugia, Italy. michela.codini@unipg.it.it.
Tommaso BeccariDepartment of Pharmaceutical Science, University of Perugia, 06123 Perugia, Italy. tommaso.beccari@unipg.it.
Francesco Saverio Ambesi-ImpiombatoDepartment of Clinical and Biological Sciences, University of Udine, 33100 Udine, Italy. ambesis@me.com.
Francesco CurcioDepartment of Clinical and Biological Sciences, University of Udine, 33100 Udine, Italy. francesco.curcio@uniud.it.
University of Perugia · ITUniversity of Udine · ITCrabion (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiation-induced damage is a complex network of interlinked signaling pathways, which may result in apoptosis, cell cycle arrest, DNA repair, and cancer. The development of thyroid cancer in response to radiation, from nuclear catastrophes to chemotherapy, has long been an object of study. A basic overview of the ionizing and non-ionizing radiation effects of the sensitivity of the thyroid gland on radiation and cancer development has been provided. In this review, we focus our attention on experiments in cell cultures exposed to ionizing radiation, ultraviolet light, and proton beams. Studies on the involvement of specific genes, proteins, and lipids are also reported. This review also describes how lipids are regulated in response to the radiation-induced damage and how they are involved in thyroid cancer etiology, invasion, and migration and how they can be used as both diagnostic markers and drug targets.

Indexed as

Radiation, IonizingAnimalsApoptosisBiomarkersHumansLipid MetabolismReactive Oxygen SpeciesSignal TransductionThyroid GlandThyroid NeoplasmsUltraviolet RaysBiomarkersReactive Oxygen Speciescancer geneslipid metabolismradiationthyroid cancer

Identifiers

PMID28445397
PMCPMC5454824
OpenAlexW2608377253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.