Evidence map›Paper›PMID 28444502›Full record

ArticleJournal of molecular neuroscience : MN2017

Preliminary Study on the Role of TMEM39A Gene in Multiple Sclerosis.

Marta Wagner, Maciej Sobczyński, Małgorzata Bilińska, Anna Pokryszko-Dragan, Małgorzata Cyrul, Piotr Kuśnierczyk, Monika Jasek

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular neuroscience : MN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Marta WagnerDepartment of Clinical Immunology, Laboratory of Immunogenetics and Tissue Immunology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, ul. Weigla 12, 53-114, Wrocław, Poland. marta_wagner@o2.pl.
Maciej SobczyńskiDepartment of Genomics, Faculty of Biotechnology, University of Wrocław, ul. Fryderyka Joliot-Curie 14a, 50-383, Wrocław, Poland.
Małgorzata BilińskaDepartment and Clinic of Neurology, Wroclaw Medical University, ul. Borowska 213, 50-566, Wrocław, Poland.
Anna Pokryszko-DraganDepartment and Clinic of Neurology, Wroclaw Medical University, ul. Borowska 213, 50-566, Wrocław, Poland.
Małgorzata CyrulDepartment and Clinic of Neurology, Wroclaw Medical University, ul. Borowska 213, 50-566, Wrocław, Poland.
Piotr KuśnierczykDepartment of Clinical Immunology, Laboratory of Immunogenetics and Tissue Immunology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, ul. Weigla 12, 53-114, Wrocław, Poland.
Monika JasekDepartment of Clinical Immunology, Laboratory of Immunogenetics and Tissue Immunology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, ul. Weigla 12, 53-114, Wrocław, Poland. jasek@iitd.pan.wroc.pl.
Wroclaw Medical University · PLPolish Academy of Sciences · PLLudwik Hirszfeld Institute of Immunology and Experimental Therapy · PLUniversity of Wrocław · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome-wide association studies (GWAS) have identified hundreds of new potential genetic risk loci associated with numerous complex diseases such as multiple sclerosis (MS). Genes which have been discovered by GWAS are now the focus of numerous ongoing studies. The goal of this study was to confirm and understand the potential role of one of such genes-transmembrane protein 39A gene (TMEM39A)-in multiple sclerosis.We showed the difference in TMEM39A messenger RNA (mRNA) expression between MS patients and controls (T

Indexed as

DNA MethylationPolymorphism, Single NucleotideFemaleHumansMaleMembrane ProteinsMultiple SclerosisPromoter Regions, GeneticRNA, MessengerMembrane ProteinsRNA, MessengerTMEM39A protein, humanMethylationmRNA expressionMultiple sclerosisPolymorphismTMEM39A

Identifiers

PMID28444502
PMCPMC5486520
OpenAlexW2608325314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.