ArticleHeart and vessels2017
Validation of numerical simulation methods in aortic arch using 4D Flow MRI.
Article in Heart and vessels, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
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Who cites it
56 citing papers in PubMed, 114 citations in OpenAlex.
- Adverse Hemodynamics in Kommerell's Diverticulum: A Comparative Case Report Linking Oscillatory Shear Index to Aortic Dissection.Clinical case reports · 2026Article
- Hemodynamic simulation in the aortic arch under anemic, diabetic, and healthy blood flow conditions using computational fluid dynamics.PloS one · 2026Article
- MRI Assessment of Energy Loss Within the Thoracic Aorta and Its Impact on Cardiac Function in Fontan Patients After Aortic Reconstruction.Journal of magnetic resonance imaging : JMRI · 2025Article
- Investigation of hemodynamic bulk flow patterns caused by aortic stenosis using a combined 4D Flow MRI-CFD framework.PLoS computational biology · 2025Article
- 4D-Flow MRI and Vector Ultrasound in the In-Vitro Evaluation of Surgical Aortic Heart Valves - a Pilot Study.Journal of cardiovascular translational research · 2025Article
- Unique Subclavian Vascular Ring Anomaly: Insights from CT Angiography.Life (Basel, Switzerland) · 2025Article
- Computational fluid dynamics modelling of hemodynamics in aortic aneurysm and dissection: a review.Frontiers in bioengineering and biotechnology · 2025Review
- Computational modeling of drug-eluting balloons in peripheral artery disease: Mechanisms, optimization, and translational insights.Computational and structural biotechnology journal · 2025Review
- Patient-specific modelling of pulmonary arterial hypertension: wall shear stress correlates with disease severity.Frontiers in bioengineering and biotechnology · 2025Article
- Four-dimensional flow magnetic resonance assessment of alcohol septal ablation for hypertrophic obstructive cardiomyopathy and surgical valve replacement for aortic valve stenosis.Frontiers in cardiovascular medicine · 2025Article
- Optimizing encoding strategies for 4D Flow MRI of mean and turbulent flow.Scientific reports · 2024Article
- Literature Survey for In-Vivo Reynolds and Womersley Numbers of Various Arteries and Implications for Compliant In-Vitro Modelling.Cardiovascular engineering and technology · 2024Review
- Medical-Surgical Implications of Branching Variation of Human Aortic Arch Known as Bovine Aortic Arch (BAA).Journal of personalized medicine · 2024Review
- Hemodynamic predictors of negative false lumen remodeling after frozen elephant trunk for acute aortic dissection.General thoracic and cardiovascular surgery · 2024Observational
- Quantitative evaluation of pulmonary hypertension using 4D flow MRI: A retrospective study.Heliyon · 2024Article
- Virtual Planning and Patient-Specific Graft Design for Aortic Repairs.Cardiovascular engineering and technology · 2024Article
- A 3D scaling law for supravalvular aortic stenosis suited for stethoscopic auscultations.Heliyon · 2024Article
- Differences in blood flow dynamics between balloon- and self-expandable valves in patients with aortic stenosis undergoing transcatheter aortic valve replacement.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Article
- A CFD-FFT approach to hemoacoustics that enables degree of stenosis prediction from stethoscopic signals.Heliyon · 2023Article
- Influence of aortic valve morphology on vortical structures and wall shear stress.Medical & biological engineering & computing · 2023Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Computational fluid dynamics (CFD) are the gold standard in studying blood flow dynamics. However, CFD results are dependent on the boundary conditions and the computation model. The purpose of this study was to validate CFD methods using comparison with actual measurements of the blood flow vector obtained with four-dimensional (4D) flow magnetic resonance imaging (MRI). 4D Flow MRI was performed on a healthy adult and a child with double-aortic arch. The aortic lumen was segmented to visualize the blood flow. The CFD analyses were performed for the same geometries based on three turbulent models: laminar, large eddy simulation (LES), and the renormalization group k-ε model (RNG k-ε). The flow-velocity vector components, namely the wall shear stress (WSS) and flow energy loss (EL), of the MRI and CFD results were compared. The flow rate of the MRI results was underestimated in small vessels, including the neck vessels. Spiral flow in the ascending aorta caused by the left ventricular twist was observed by MRI. Secondary flow distal to the aortic arch was well realized in both CFD and MRI. The average correlation coefficients of the velocity vector components of MRI and CFD for the child were the highest for the RNG k-ε model (0.530 in ascending aorta, 0.768 in the aortic arch, 0.584 in the descending aorta). The WSS and EL values of MRI were less than half of those of CFD, but the WSS distribution patterns were quite similar. The WSS and EL estimates were higher in RNG k-ε and LES than in the laminar model because of eddy viscosity. The CFD computation realized accurate flow distal to the aortic arch, and the WSS distribution was well simulated compared to actual measurement using 4D Flow MRI. However, the helical flow was not simulated in the ascending aorta. The accuracy was enhanced by using the turbulence model, and the RNG k-ε model showed the highest correlation with 4D Flow MRI.
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