Evidence map›Paper›PMID 28444488›Full record

Trial reportDysphagia2017

Prophylactic Swallow Therapy for Patients with Head and Neck Cancer Undergoing Chemoradiotherapy: A Randomized Trial.

Barbara Pisano Messing, Elizabeth C Ward, Cathy L Lazarus, Melissa Kim, Xian Zhou, Jessica Silinonte, Dorothy Gold, Karen Harrer, Karen Ulmer, Samantha Merritt and 5 more

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Dysphagia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 8 pooled it
14.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 8 syntheses or guidelines pooled it, 116 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Barbara Pisano MessingThe Milton J Dance, Jr. Head and Neck Center, Johns Hopkins Head & Neck Surgery, Johns Hopkins Voice Center, 6569 N. Charles Street, PPW Suite 401, Baltimore, MD, 21204, USA. bmessing@gbmc.org.
Elizabeth C WardSchool of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, QLD, Australia.
Cathy L LazarusIcahn School of Medicine at Mount Sinai, Thyroid Head and Neck Research Center, Thyroid Head and Neck Cancer (THANC) Foundation, Department of Otolaryngology Head & Neck Surgery, Mount Sinai Beth Israel, New York, USA.
Melissa KimThe Milton J Dance, Jr. Head and Neck Center, Johns Hopkins Head & Neck Surgery, Johns Hopkins Voice Center, 6569 N. Charles Street, PPW Suite 401, Baltimore, MD, 21204, USA.
Xian ZhouThe Division of Biostatistics and Bioinformatics at the Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, USA.
Jessica SilinonteThe Milton J Dance, Jr. Head and Neck Center, Johns Hopkins Head & Neck Surgery, Johns Hopkins Voice Center, 6569 N. Charles Street, PPW Suite 401, Baltimore, MD, 21204, USA.
Dorothy GoldThe Milton J Dance, Jr. Head and Neck Center, Johns Hopkins Head & Neck Surgery, Johns Hopkins Voice Center, 6569 N. Charles Street, PPW Suite 401, Baltimore, MD, 21204, USA.
Karen HarrerThe Milton J Dance, Jr. Head and Neck Center, Johns Hopkins Head & Neck Surgery, Johns Hopkins Voice Center, 6569 N. Charles Street, PPW Suite 401, Baltimore, MD, 21204, USA.
Karen UlmerThe Milton J Dance, Jr. Head and Neck Center, Johns Hopkins Head & Neck Surgery, Johns Hopkins Voice Center, 6569 N. Charles Street, PPW Suite 401, Baltimore, MD, 21204, USA.
Samantha MerrittThe Milton J Dance, Jr. Head and Neck Center, Johns Hopkins Head & Neck Surgery, Johns Hopkins Voice Center, 6569 N. Charles Street, PPW Suite 401, Baltimore, MD, 21204, USA.
Geoffrey NeunerThe Milton J Dance, Jr. Head and Neck Center, Johns Hopkins Head & Neck Surgery, Johns Hopkins Voice Center, 6569 N. Charles Street, PPW Suite 401, Baltimore, MD, 21204, USA.
Marshall LevineThe Milton J Dance, Jr. Head and Neck Center, Johns Hopkins Head & Neck Surgery, Johns Hopkins Voice Center, 6569 N. Charles Street, PPW Suite 401, Baltimore, MD, 21204, USA.
Ray BlancoThe Milton J Dance, Jr. Head and Neck Center, Johns Hopkins Head & Neck Surgery, Johns Hopkins Voice Center, 6569 N. Charles Street, PPW Suite 401, Baltimore, MD, 21204, USA.
John SaundersThe Milton J Dance, Jr. Head and Neck Center, Johns Hopkins Head & Neck Surgery, Johns Hopkins Voice Center, 6569 N. Charles Street, PPW Suite 401, Baltimore, MD, 21204, USA.
Joseph CalifanoThe Milton J Dance, Jr. Head and Neck Center, Johns Hopkins Head & Neck Surgery, Johns Hopkins Voice Center, 6569 N. Charles Street, PPW Suite 401, Baltimore, MD, 21204, USA.
Johns Hopkins University · USThyroid Head and Neck Cancer Foundation · USUniversity of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence supporting prophylactic swallow exercises for patients with head and neck cancer (HNC) has not been universally demonstrated. This RCT examined diet level, feeding tube use, swallow function, and quality of life (QOL) of patients undergoing chemoradiotherapy who performed prophylactic swallowing exercises. Sixty HNC patients were randomized into exercise versus control groups. Swallowing, oromotor, toxicity, and QOL data were recorded (baseline, 3, 6, 12, 24 months). Physiological swallow function was examined at baseline and 3 months. Swallow exercises were completed twice daily. Oral intake at 3 months was 10% better in the exercise group, which was not statistically significant (p = 0.49). Significant (p < 0.05) differences in secondary outcomes including oromotor function, pharyngeal impairment, oral pharyngeal swallow efficiency, and incisal opening were noted at early time points (3-6 months) in the exercise group. Possible positive early improvements in swallow function are associated with swallowing exercises, although these improvements are not significant longer term.

Indexed as

AdultAgedChemoradiotherapyDeglutitionDeglutition DisordersEatingExercise TherapyFemaleHead and Neck NeoplasmsHumansMaleMiddle AgedMouthQuality of LifeTreatment OutcomeChemoradiationDysphagiaProphylactic exercisesQuality of lifeSwallowing

Identifiers

PMID28444488
PMCPMC5515964
OpenAlexW2609894614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.