ArticleEinstein (Sao Paulo, Brazil)
Interictal abnormal fMRI activation of visual areas during a motor task cued by visual stimuli in migraine.
Article in Einstein (Sao Paulo, Brazil). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- fMRI Insights into Visual Cortex Dysfunction as a Biomarker for Migraine with Aura.Neurology international · 2025Review
- Impaired intrinsic functional connectivity between the thalamus and visual cortex in migraine without aura.The journal of headache and pain · 2019Article
- Abnormal functional connectivity under somatosensory stimulation in migraine: a multi-frequency magnetoencephalography study.The journal of headache and pain · 2019Article
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7 authors.
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Abstract
objectiveTo assess changes in blood-oxygen-level-dependent activity after light deprivation compared to regular light exposure in subjects with migraine in the interictal state and in controls.
methodsTen subjects with migraine and ten controls participated in two sessions of functional magnetic resonance imaging. In each session, they performed a finger-tapping task with the right hand, cued by visual stimuli. They were scanned before and after 30 minutes of light deprivation or light exposure. In subjects with migraine, functional magnetic resonance imaging was performed interictally. Analysis of variance was made with the factors time (before or after), session (light deprivation or exposure), and group (migraine or control).
resultsThere were significant "group" effects in a cluster in the bilateral cuneus encompassing the superior border of the calcarine sulcus and extrastriate cortex. There were no significant effects of "time", "session", or interactions between these factors.
conclusionThe main result of this study is consistent with aberrant interictal processing of visual information in migraine. Light deprivation did not modulate functional magnetic resonance imaging activity in subjects with or without migraine. OBJETIVO: Avaliar mudanças na atividade cerebral por meio de ressonância magnética funcional após privação luminosa comparada à exposição à luz, em indivíduos com enxaqueca no estado interictal e em controles. MÉTODOS: Dez indivíduos com enxaqueca e dez controles participaram de duas sessões de ressonância magnética funcional. Em cada sessão, realizaram uma tarefa motora com a mão direita guiada por estímulos visuais. Foram colhidas imagens antes e após 30 minutos de privação luminosa ou exposição à luz. Em indivíduos com enxaqueca, a ressonância funcional foi realizada no período interictal. Foi feita a análise de variância com fatores tempo (antes ou depois), sessão (privação ou exposição à luz) e grupo (enxaqueca ou controle). RESULTADOS: Houve efeitos significativos de "grupo" em uma área no cúneo bilateral, incluindo a borda superior do sulco calcarino e o córtex extraestriado. Não houve efeitos significativos de "tempo", "sessão" ou interações entre estes fatores. CONCLUSÃO: O principal resultado deste estudo sugere um processamento interictal anormal das informações visuais em indivíduos com enxaqueca. A privação luminosa não modulou a atividade na ressonância magnética funcional em indivíduos com ou sem enxaqueca.
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