ArticleBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica2017
Diagnostic and prognostic value of procalcitonin for early intracranial infection after craniotomy.
Article in Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Diagnostic accuracy of serum procalcitonin for intracranial infection in adults: A systematic review and meta-analysis.Medicine · 2026Pooled it
- Intraoperative Cytokines and Postcraniotomy Infection in Benign Brain Tumors: An Exploratory Prospective Study.Journal of clinical medicine · 2026Article
- Development and validation of a diagnostic nomogram for post-neurosurgical bacterial meningitis.BMC neurology · 2026Article
- Multi-Route Administration Therapy for IntracranialInternational medical case reports journal · 2026Article
- Diagnostic and prognostic value of combined cerebrospinal fluid parameters for post-neurosurgical intracranial infection in brain tumor patients.Scientific reports · 2025Article
- Serum amyloid A and proadrenomedullin as early markers in critically ill children with sepsis.Clinical and experimental pediatrics · 2025Article
- A novel nomogram for predicting prolonged disorders of consciousness in severe supratentorial hypertensive intracerebral hemorrhage patients.Scientific reports · 2025Article
- Procalcitonin as a biomarker for postoperative pneumonia: a study on dynamics following cardiopulmonary bypass in adults.BMC cardiovascular disorders · 2025Article
- Combination value of cell index, CSF PCT, and CSF IL-6 for intracranial infection diagnosis after neurosurgery.Scientific reports · 2025Article
- Robot assisted stereotactic surgery improves hematoma evacuation in intracerebral hemorrhage compared to frame based method.Scientific reports · 2025Article
- Development and validation of a nomogram for predicting intracranial infection after intracranial aneurysm surgery.Frontiers in neurology · 2025Article
- Clinical benefit of robot-assisted minimally invasive stereotactic aspiration/drainage in hypertensive intracerebral hemorrhage.American journal of translational research · 2025Article
- The diagnostic and prognostic value of heparin-binding protein in cerebrospinal fluid for patients with intracranial infections.European journal of medical research · 2024Article
- A prospective study of nanopore-targeted sequencing in the diagnosis of central nervous system infections.Microbiology spectrum · 2024Article
- Detecting Diabetic Ketoacidosis with Infection: Combating a Life-Threatening Emergency with Practical Diagnostic Tools.Diagnostics (Basel, Switzerland) · 2023Review
- Systemic Infection Predictive Value of Procalcitonin to Lactic Acid Ratio in Diabetes Ketoacidosis Patients.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- Analysis of Cerebrospinal Fluid Routine Biochemical Level, Pathogenic Bacteria Distribution, and Risk Factors in Patients with Secondary Intracranial Infection after Brain Tumor Surgery.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Combining modified Graeb score and intracerebral hemorrhage score to predict poor outcome in patients with spontaneous intracerebral hemorrhage undergoing surgical treatment.Frontiers in neurology · 2022Article
- The risk factors of intracranial infection in patients with intracerebral hemorrhage undergone hematoma puncture: what should we care.BMC infectious diseases · 2020Article
- Application value analysis of magnetic resonance imaging and computed tomography in the diagnosis of intracranial infection after craniocerebral surgery.World journal of clinical cases · 2020Article
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Authors and funding
2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Intracranial infection is a common clinical complication after craniotomy. We aimed to explore the diagnostic and prognostic value of dynamic changing procalcitonin (PCT) in early intracranial infection after craniotomy. A prospective study was performed on 93 patients suspected of intracranial infection after craniotomy. Routine peripheral venous blood was collected on the day of admission, and C reactive protein (CRP) and PCT levels were measured. Cerebrospinal fluid (CSF) was collected for routine biochemical, PCT and culture assessment. Serum and CSF analysis continued on days 1, 2, 3, 5, 7, 9, and 11. The patients were divided into intracranial infection group and non-intracranial infection group; intracranial infection group was further divided into infection controlled group and infection uncontrolled group. Thirty-five patients were confirmed with intracranial infection after craniotomy according to the diagnostic criteria. The serum and cerebrospinal fluid PCT levels in the infected group were significantly higher than the non-infected group on day 1 (P<0.05, P<0.01). The area under curve of receiver operating characteristics was 0.803 for CSF PCT in diagnosing intracranial infection. The diagnostic sensitivity and specificity of CSF PCT was superior to other indicators. The serum and CSF PCT levels have potential value in the early diagnosis of intracranial infection after craniotomy. Since CSF PCT levels have higher sensitivity and specificity, dynamic changes in this parameter could be used for early detection of intracranial infection after craniotomy, combined with other biochemical indicators.
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