ReviewMemorias do Instituto Oswaldo Cruz2017
Zika puzzle in Brazil: peculiar conditions of viral introduction and dissemination - A Review.
Review in Memorias do Instituto Oswaldo Cruz, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Imperfect diagnosis: The truncated legacies of Zika testing.Social studies of science · 2021Article
- Is the ZIKV Congenital Syndrome and Microcephaly Due to Syndemism with Latent Virus Coinfection?Viruses · 2021Review
- Extracts of Amazonian Fungi With Larvicidal Activities AgainstFrontiers in microbiology · 2021Article
- LowViruses · 2020Article
- Vector Competence ofPathogens (Basel, Switzerland) · 2020Article
- Dengue Infection in Children in Fortaleza, Brazil: A 3-Year School-Based Prospective Cohort Study.The American journal of tropical medicine and hygiene · 2020Article
- Spatial modelling of the infestation indices of Aedes aegypti: an innovative strategy for vector control actions in developing countries.Parasites & vectors · 2020Article
- Persistent Zika Virus Infection Associated with Early Fetal Demise: A Case Report.Open journal of obstetrics and gynecology · 2019Article
- Electoral incentives to combat mosquito-borne illnesses: Experimental evidence from Brazil.World development · 2019Article
- Cell Death And Zika Virus: An Integrated Network Of The Mechanisms Of Cell Injury.Infection and drug resistance · 2019Article
- Zika virus infection in human placental tissue explants is enhanced in the presence of dengue virus antibodies in-vitro.Emerging microbes & infections · 2018Article
- Zika infection decreases Aedes aegypti locomotor activity but does not influence egg production or viability.Memorias do Instituto Oswaldo Cruz · 2018Article
- NS1 codon usage adaptation to humans in pandemic Zika virus.Memorias do Instituto Oswaldo Cruz · 2018Article
- Culex quinquefasciatus mosquitoes do not support replication of Zika virus.The Journal of general virology · 2018Article
- The Zika Virus Epidemic in Brazil: From Discovery to Future Implications.International journal of environmental research and public health · 2018Review
- Observational
- Palliative Care in Congenital Syndrome of the Zika Virus Associated with Hospitalization and Emergency Consultation: Palliative Care and Congenital Syndrome of Zika.Journal of tropical medicine · 2018Article
- Zika virus infection modulates the bacterial diversity associated with Aedes aegypti as revealed by metagenomic analysis.PloS one · 2018Article
- Zika virus can be venereally transmitted between Aedes aegypti mosquitoes.Parasites & vectors · 2017Article
- Culex quinquefasciatus from areas with the highest incidence of microcephaly associated with Zika virus infections in the Northeast Region of Brazil are refractory to the virus.Memorias do Instituto Oswaldo Cruz · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This article discusses the peculiar conditions that favoured the unexpected introduction of Zika virus into the poorest northeastern region of Brazil in 2015, its speed of transmission to other Brazilian states, other Latin American countries and other regions, and the severity of related neurological disorders in newborns and adults. Contrasting with evidence that Zika had so far caused only mild cases in humans in the last six decades, the epidemiological scenario of this outbreak in Brazil indicates dramatic health effects: in 2015, an increase of 20-fold in notified cases of microcephaly and/or central nervous system (CNS) alterations suggestive of Zika congenital infection, followed by an exponential increase in 2016, with 2366 cumulative cases confirmed in the country by the end of December 2016. A significant increase in Guillain-Barré syndrome in adults has also been reported. Factors involved in viral dissemination, neural pathogenesis and routes of transmission in Brazil are examined, such as the role of social and environmental factors and the controversies involved in the hypothesis of antibody-dependent enhancement, to explain the incidence of congenital Zika syndrome in Brazil. Responses to the Zika outbreak and the development of new products are also discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.