ArticleMemorias do Instituto Oswaldo Cruz2017
Experimental toxocariasis in BALB/c mice: relationship between parasite inoculum and the IgG immune response.
Article in Memorias do Instituto Oswaldo Cruz, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- From models to medicine: systematic development and evaluation of animal models forFrontiers in immunology · 2026Review
- Analysis of Seroreactivity and Seropositivity in Balb/c Mice Experimentally Infected with Toxocara canis Using Two Recombinant (rTc-CTL-1 and rTES-120) Antigens.Acta parasitologica · 2025Article
- Immunogenic mapping of potential epitopes from Tc-CTL-1 for the diagnosis of murine toxocariasis.Memorias do Instituto Oswaldo Cruz · 2025Article
- An evaluation of techniques to diagnoseBrazilian journal of veterinary medicine · 2024Article
- Article
- Larva migrans in BALB/c mice experimentally infected with Toxocara cati ensured by PCR assay.BMC veterinary research · 2022Article
- Toxocara canis 30-35 kDa excretory-secretory antigen is an important marker in mice challenged by inocula containing different parasite load levels.Revista do Instituto de Medicina Tropical de Sao Paulo · 2022Article
- Human Toxocariasis: 2010 to 2020 Contributions from Brazilian Researchers.Research and reports in tropical medicine · 2021Review
- "Begging the Question"-DoesPathogens (Basel, Switzerland) · 2020Article
- Detection and Evaluation of Antibody Response to a Baylisascaris-Specific Antigen in Rodent Hosts with the Use of Western Blotting and Elisa.The Journal of parasitology · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BALB/c mice were inoculated with 5-500 Toxocara canis infective eggs, and bled at 15-120 days post infection (dpi) to evaluate the dynamics of IgG antibody response and larvae distribution. Positive results were observed in all occasions for every inoculum, and a direct proportional relationship between antibody detection and the parasitic load was observed. In samples collected at 60 dpi, detection of IgG was more intense, especially with the 50 and 500 egg doses; also, a correlation between antibody level and egg count was observed with these two inocula. At 120 dpi, a decrease in antibody titer was observed for all groups; and at the end of the experiment, larvae were recovered from carcass, liver and brain. In the liver, larvae were only found in mice inoculated with 500 T. canis eggs. In carcasses, these were recovered in all groups, and the group inoculated with 50 eggs showed the highest percentage of larvae in the brain.
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