Evidence map›Paper›PMID 28443626›Full record

ArticleNature communications2017

Nanodiamond-enhanced MRI via in situ hyperpolarization.

David E J Waddington, Mathieu Sarracanie, Huiliang Zhang, Najat Salameh, David R Glenn, Ewa Rej, Torsten Gaebel, Thomas Boele, Ronald L Walsworth, David J Reilly and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Temperature-Dependent Dynamic Nuclear Polarization of Diamond.The journal of physical chemistry. C, Nanomaterials and interfaces · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Recent Developments of Nanodiamond Quantum Sensors for Biological Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Hyperpolarized relaxometry based nuclear TNature communications · 2019
    Article
  18. Review Article: Synthesis, properties, and applications of fluorescent diamond particles.Journal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B · 2019
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

David E J WaddingtonA.A. Martinos Center for Biomedical Imaging, Suite 2301, 149 13th Street, Charlestown, Massachusetts 02129, USA.
Mathieu SarracanieA.A. Martinos Center for Biomedical Imaging, Suite 2301, 149 13th Street, Charlestown, Massachusetts 02129, USA.
Huiliang ZhangDepartment of Physics, Harvard University, 17 Oxford Street, Cambridge, Massachusetts 02138, USA.
Najat SalamehA.A. Martinos Center for Biomedical Imaging, Suite 2301, 149 13th Street, Charlestown, Massachusetts 02129, USA.
David R GlennDepartment of Physics, Harvard University, 17 Oxford Street, Cambridge, Massachusetts 02138, USA.
Ewa RejARC Centre of Excellence for Engineered Quantum Systems, School of Physics, University of Sydney, Sydney, New South Wales 2006, Australia.
Torsten GaebelARC Centre of Excellence for Engineered Quantum Systems, School of Physics, University of Sydney, Sydney, New South Wales 2006, Australia.
Thomas BoeleARC Centre of Excellence for Engineered Quantum Systems, School of Physics, University of Sydney, Sydney, New South Wales 2006, Australia.
Ronald L WalsworthDepartment of Physics, Harvard University, 17 Oxford Street, Cambridge, Massachusetts 02138, USA.
David J ReillyARC Centre of Excellence for Engineered Quantum Systems, School of Physics, University of Sydney, Sydney, New South Wales 2006, Australia.
Matthew S RosenA.A. Martinos Center for Biomedical Imaging, Suite 2301, 149 13th Street, Charlestown, Massachusetts 02129, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanodiamonds are of interest as nontoxic substrates for targeted drug delivery and as highly biostable fluorescent markers for cellular tracking. Beyond optical techniques, however, options for noninvasive imaging of nanodiamonds in vivo are severely limited. Here, we demonstrate that the Overhauser effect, a proton-electron polarization transfer technique, can enable high-contrast magnetic resonance imaging (MRI) of nanodiamonds in water at room temperature and ultra-low magnetic field. The technique transfers spin polarization from paramagnetic impurities at nanodiamond surfaces to

Indexed as

NanodiamondsElectronsElectron Spin Resonance SpectroscopyMagnetic FieldsMagnetic Resonance ImagingProton Magnetic Resonance SpectroscopyProtonsNanodiamondsProtons

Identifiers

PMID28443626
PMCPMC5414045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.