Evidence map›Paper›PMID 28443606›Full record

ArticleLeukemia2017

Genotype-outcome correlations in pediatric AML: the impact of a monosomal karyotype in trial AML-BFM 2004.

M Rasche, C von Neuhoff, M Dworzak, J-P Bourquin, J Bradtke, G Göhring, G Escherich, G Fleischhack, N Graf, B Gruhn and 12 more

Open access · hybridAbstract read
In one paragraph

Article in Leukemia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Straight to the Point-The Novel Strategies to Cure Pediatric AML.International journal of molecular sciences · 2022
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 12 institutions in 4 countries.

M RascheDepartment of Pediatric Hematology/Oncology, Pediatrics III, University Hospital of Essen, Essen, Germany.
C von NeuhoffDepartment of Pediatric Hematology/Oncology, Pediatrics III, University Hospital of Essen, Essen, Germany.
M DworzakDepartment of Pediatrics, St Anna Children's Hospital and Children's Cancer Research Institute, Medical University of Vienna, Vienna, Austria.
J-P BourquinDepartment of Pediatric Oncology, University Children's Hospital Zurich, Zurich, Switzerland.
J BradtkeInstitute of Pathology, University Hospital Giessen and Marburg, Marburg, Germany.
G GöhringInstitute of Human Genetics, Hannover Medical School, Hannover, Germany.
G EscherichClinic of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
G FleischhackDepartment of Pediatric Hematology/Oncology, Pediatrics III, University Hospital of Essen, Essen, Germany.
N GrafDepartment of Pediatric Oncology and Hematology, Medical School, Saarland University, Homburg, Germany.ORCID 0000-0002-2248-323X
B GruhnDepartment of Pediatrics, Jena University Hospital, Jena, Germany.
O A HaasLabdia, Children's Cancer Research Institute, Vienna, Austria.
T KlingebielDepartment of Pediatric Hematology, Oncology and Hemostaseology, Hospital for Children and Adolescents, University Hospital of Frankfurt/Main, Goethe-University Frankfurt/Main, Frankfurt/Main, Germany.
B KremensDepartment of Pediatric Hematology/Oncology, Pediatrics III, University Hospital of Essen, Essen, Germany.
T LehrnbecherDepartment of Pediatric Hematology, Oncology and Hemostaseology, Hospital for Children and Adolescents, University Hospital of Frankfurt/Main, Goethe-University Frankfurt/Main, Frankfurt/Main, Germany.
A von StackelbergDepartment of Pediatric Oncology/Hematology, Charité Universitätsmedizin Berlin, Berlin, Germany.
J TchindaDepartment of Pediatric Oncology, University Children's Hospital Zurich, Zurich, Switzerland.
Z ZemanovaCenter of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital and First Faculty of Medicine, Charles University in Prague, Czech Republic.
C ThiedeDepartment of Medicine I, University of Dresden, Dresden, Germany.
N von NeuhoffDepartment of Pediatric Hematology/Oncology, Pediatrics III, University Hospital of Essen, Essen, Germany.
M ZimmermannPediatric Hematology-Oncology, Hannover Medical School, Hannover, Germany.
U CreutzigPediatric Hematology-Oncology, Hannover Medical School, Hannover, Germany.
D ReinhardtDepartment of Pediatric Hematology/Oncology, Pediatrics III, University Hospital of Essen, Essen, Germany.
Essen University Hospital · DEMedizinische Hochschule Hannover · DEGoethe University Frankfurt · DESt Anna Children's Hospital · ATUniversity Children's Hospital Zurich · CHCharité - Universitätsmedizin Berlin · DECharles University · CZJena University Hospital · DESaarland University · DETechnische Universität Dresden · DEUniversität Hamburg · DEUniversitätsklinikum Gießen und Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted a cytogenetic analysis of 642 children with de novo acute myeloid leukemia (AML) treated on the AML-Berlin-Frankfurt-Münster (BFM) 04 protocol to determine the prognostic value of specific chromosomal aberrations including monosomal (MK

Indexed as

Genetic VariationGenotypeChromosome AberrationsChromosomes, Human, Pair 7Clinical Trials as TopicFemaleHumansKaryotypeLeukemia, Myeloid, AcuteMaleMonosomyMutationPrognosisSurvival Analysis

Identifiers

PMID28443606
PMCPMC5729330
OpenAlexW2609323007

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.