Evidence map›Paper›PMID 28443270›Full record

ArticleFrontiers in pediatrics2017

Brain Lesions among Orally Fed and Gastrostomy-Fed Dysphagic Preterm Infants: Can Routine Qualitative or Volumetric Quantitative Magnetic Resonance Imaging Predict Feeding Outcomes?

Nasser H Kashou, Irfaan A Dar, Mohamed A El-Mahdy, Charles Pluto, Mark Smith, Ish K Gulati, Warren Lo, Sudarshan R Jadcherla

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. A Unique Clinical Tool for the Evaluation of Oral Feeding Skills in Infants.Canadian journal of occupational therapy. Revue canadienne d'ergotherapie · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Nasser H KashouWright State University, Image Analysis Lab, Dayton, OH, USA.
Irfaan A DarWright State University, Image Analysis Lab, Dayton, OH, USA.
Mohamed A El-MahdyInnovative Research Program in Neonatal and Infant Feeding Disorders, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Charles PlutoDepartment of Radiology, Nationwide Children's Hospital, Columbus, OH, USA.
Mark SmithDepartment of Radiology, Nationwide Children's Hospital, Columbus, OH, USA.
Ish K GulatiInnovative Research Program in Neonatal and Infant Feeding Disorders, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Warren LoDepartment of Radiology, Nationwide Children's Hospital, Columbus, OH, USA.
Sudarshan R JadcherlaInnovative Research Program in Neonatal and Infant Feeding Disorders, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Nationwide Children's Hospital · USWright State University · USInnovative Research (United States) · US

Funding

Pathophysiology of Aerodigestive Reflexes in InfantsR01DK068158 · NIDDK · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI JADCHERLA, SUDARSHAN R · 2006 to 2016
$3.7M
NIDDK NIH HHS R01 DK068158
6 · The paper itself

Abstract

introductionThe usefulness of qualitative or quantitative volumetric magnetic resonance imaging (MRI) in early detection of brain structural changes and prediction of adverse outcomes in neonatal illnesses warrants further investigation. Our aim was to correlate certain brain injuries and the brain volume of feeding-related cortical and subcortical regions with feeding method at discharge among preterm dysphagic infants. MATERIALS AND

methodsUsing a retrospective observational study design, we examined MRI data among 43 (22 male; born at 31.5 ± 0.8 week gestation) infants who went home on oral feeding or gastrostomy feeding (G-tube). MRI scans were segmented, and volumes of brainstem, cerebellum, cerebrum, basal ganglia, thalamus, and vermis were quantified, and correlations were made with discharge feeding outcomes. Chi-squared tests were used to evaluate MRI findings vs. feeding outcomes. ANCOVA was performed on the regression model to measure the association of maturity and brain volume between groups.

resultsOut of 43 infants, 44% were oral-fed and 56% were G-tube fed at hospital discharge (but not at time of the study). There was no relationship between qualitative brain lesions and feeding outcomes. Volumetric analysis revealed that cerebellum was greater (

conclusionThis study concludes that neither qualitative nor quantitative volumetric MRI findings correlate with feeding outcomes. Understanding the complexity of swallowing and feeding difficulties in infants warrants a comprehensive and in-depth functional neurological assessment.

Indexed as

cerebellumdysphagiafeedinginfantsegmentationvolumetric

Identifiers

PMID28443270
PMCPMC5385332
OpenAlexW2604775827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.