Evidence map›Paper›PMID 28443062›Full record

ArticleFrontiers in neurology2017

Somatosensory Misrepresentation Associated with Chronic Pain: Spatiotemporal Correlates of Sensory Perception in a Patient following a Complex Regional Pain Syndrome Spread.

Lars Büntjen, Jens-Max Hopf, Christian Merkel, Jürgen Voges, Stefan Knape, Hans-Jochen Heinze, Mircea Ariel Schoenfeld

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  7. Phantom limb pain: A literature review.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Lars BüntjenDepartment of Stereotactic Neurosurgery, Otto-von-Guericke University, Magdeburg, Germany.
Jens-Max HopfDepartment of Stereotactic Neurosurgery, Otto-von-Guericke University, Magdeburg, Germany.
Christian MerkelDepartment of Neurology, Otto-von-Guericke University, Magdeburg, Germany.
Jürgen VogesDepartment of Stereotactic Neurosurgery, Otto-von-Guericke University, Magdeburg, Germany.
Stefan KnapeDepartment of Neurology, Otto-von-Guericke University, Magdeburg, Germany.
Hans-Jochen HeinzeLeibniz Institute for Neurobiology, Magdeburg, Germany.
Mircea Ariel SchoenfeldLeibniz Institute for Neurobiology, Magdeburg, Germany.
Otto-von-Guericke University Magdeburg · DEKliniken Schmieder · DELeibniz Institute for Neurobiology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic pain is suggested to be linked to reorganization processes in the sensorimotor cortex. In the current study, the somatosensory representation of the extremities was investigated in a patient with a complex regional pain syndrome (CRPS) that initially occurred in the right hand and arm and spread later into the left hand and right leg. After the spread, magnetoencephalographic recordings in conjunction with somatosensory stimulation revealed that the clinical symptoms were associated with major changes in the primary somatosensory representation. Tactile stimulation of body parts triggering CRPS-related pain elicited activity located in the left primary somatosensory region corresponding to the right hand representation, where the CRPS initially appeared. Solely the unaffected left foot was observed to have a regular S1 representation. The pain distribution pattern was matching the cortical somatosensory misrepresentation suggesting that cortical reorganization processes might contribute and possibly underlie the development and spread of the CRPS.

Indexed as

complex regional pain syndromecortical reorganizationmagnetencephalographypain spreadprimary somatosensory cortex

Identifiers

PMID28443062
PMCPMC5385457
OpenAlexW2605536362

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.