ArticleFrontiers in aging neuroscience2017
Increased Diagnostic Accuracy of Digital vs. Conventional Clock Drawing Test for Discrimination of Patients in the Early Course of Alzheimer's Disease from Cognitively Healthy Individuals.
Article in Frontiers in aging neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Digital Tools for Mild Cognitive Impairment: A Systematic Review and Meta-analysis of Diagnostic Accuracy and Methodological Challenges.Neuropsychology review · 2026Pooled it
- Alzheimer's early detection in post-acute COVID-19 syndrome: a systematic review and expert consensus on preclinical assessments.Frontiers in aging neuroscience · 2023Pooled it
- Evaluation of Digital Drawing Tests and Paper-and-Pencil Drawing Tests for the Screening of Mild Cognitive Impairment and Dementia: A Systematic Review and Meta-analysis of Diagnostic Studies.Neuropsychology review · 2022Pooled it
- Diagnostic accuracy of digital clock drawing test for Alzheimer disease and mild cognitive impairment.NPJ digital medicine · 2026Article
- Predicting cognitive impairment using novel functional features of spatial proximity and circularity in the digital clock drawing test.medRxiv : the preprint server for health sciences · 2026Article
- Artificial Intelligence-Enhanced Multi-Algorithm R Shiny Application for Predictive Modeling and Analytics: Case Study of Alzheimer Disease Diagnostics.JMIR aging · 2025Article
- Effectiveness of digital screening tools in detecting cognitive impairment among community-dwelling elderly in Northern China: A large cohort study.The journal of prevention of Alzheimer's disease · 2025Article
- Differential cognitive functioning in the digital clock drawing test in AD-MCI and PD-MCI populations.Frontiers in neuroscience · 2025Article
- The Potential of Automated Assessment of Cognitive Function Using Non-Neuroimaging Data: A Systematic Review.Journal of clinical medicine · 2024Review
- Detection of Mild Cognitive Impairment Through Hand Motor Function Under Digital Cognitive Test: Mixed Methods Study.JMIR mHealth and uHealth · 2024Article
- A tablet-based multi-dimensional drawing system can effectively distinguish patients with amnestic MCI from healthy individuals.Scientific reports · 2024Article
- Detection of Alzheimer's Disease Using Logistic Regression and Clock Drawing Errors.Brain sciences · 2023Article
- Conventional clock drawing tests have low to moderate reliability and validity for detecting subtle cognitive impairments in community-dwelling older adults.Frontiers in aging neuroscience · 2023Article
- Digital Cognitive Biomarker for Mild Cognitive Impairments and Dementia: A Systematic Review.Journal of clinical medicine · 2022Review
- A Computerized Cognitive Test Battery for Detection of Dementia and Mild Cognitive Impairment: Instrument Validation Study.JMIR aging · 2022Article
- Automated scoring for a Tablet-based Rey Figure copy task differentiates constructional, organisational, and motor abilities.Scientific reports · 2021Article
- Association of Digital Clock Drawing With PET Amyloid and Tau Pathology in Normal Older Adults.Neurology · 2021Article
- Article
- Digital Technology Differentiates Graphomotor and Information Processing Speed Patterns of Behavior.Journal of Alzheimer's disease : JAD · 2021Article
- Integrative Base Ontology for the Research Analysis of Alzheimer's Disease-Related Mild Cognitive Impairment.Frontiers in neuroinformatics · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The conventional Clock Drawing Test (cCDT) is a rapid and inexpensive screening tool for detection of moderate and severe dementia. However, its usage is limited due to poor diagnostic accuracy especially in patients with mild cognitive impairment (MCI). The diagnostic value of a newly developed digital Clock Drawing Test (dCDT) was evaluated and compared with the cCDT in 20 patients with early dementia due to AD (eDAT), 30 patients with amnestic MCI (aMCI) and 20 cognitively healthy controls (HCs). Parameters assessed by dCDT were time while transitioning the stylus from one stroke to the next above the surface (i.e., time-in-air), time the stylus produced a visible stroke (i.e., time-on-surface) and total-time during clock drawing. Receiver-operating characteristic (ROC) curves were calculated and logistic regression analyses have been conducted for statistical analysis. Using dCDT, time-in-air was significantly increased in eDAT (70965.8 ms) compared to aMCI (54073.7 ms;
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.