ArticleJournal of pain research2017
Postoperative pain and patient-controlled epidural analgesia-related adverse effects in young and elderly patients: a retrospective analysis of 2,435 patients.
Article in Journal of pain research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- The efficacy and safety of selective COX-2 inhibitors for postoperative pain management in patients after total knee/hip arthroplasty: a meta-analysis.Journal of orthopaedic surgery and research · 2020Pooled it
- Thoracic epidural analgesia (TEA) versus patient-controlled analgesia (PCA) in laparoscopic colectomy: a systematic review and meta-analysis.International journal of colorectal disease · 2019Pooled it
- The effect of intravenous lidocaine infusion on subarachnoid anesthesia in patients undergoing total knee replacement: a randomised controlled trial.Journal of anesthesia · 2025Trial
- Comparison of Postoperative Pain and Adverse Effects between Variable-Rate Feedback Infusion and Conventional Fixed-Rate Basal Infusion Modes of Patient-Controlled Epidural Analgesia following Open Gastrectomy: A Randomized Controlled Trial.International journal of environmental research and public health · 2021Trial
- Multimodal analgesia protocol for pain management after total knee arthroplasty: comparison of three different regional analgesic techniques.Journal of musculoskeletal & neuronal interactions · 2021Trial
- From labor to surgery: expanding the role of programmed intermittent epidural bolus beyond obstetric.Anesthesia and pain medicine · 2026Review
- Predictive Clinical Factors of Pain-Related Quality of Recovery Following Elective Gastrointestinal and Hepato-Pancreato-Biliary Surgery: An Observational Study in Norway.Journal of pain research · 2025Article
- Predicting risk factors for acute pain after hepatobiliary and pancreatic surgery: an observational case control study.BMJ open · 2024Observational
- Article
- IPACK Block Efficacy for Acute Pain Management after Total Knee Replacement: A Review.Current pain and headache reports · 2024Review
- A Retrospective Comparison of Clinical Efficacy between Multimodal Analgesia and Patient-Controlled Epidural Analgesia in Patients Undergoing Total Knee Arthroplasty.Medicina (Kaunas, Lithuania) · 2023Article
- Early chest drain removal on the day of uniportal thoracoscopic segmentectomy.General thoracic and cardiovascular surgery · 2023Article
- Risk factors for discontinuation of intravenous patient-controlled analgesia after general surgery: a retrospective cohort study.Scientific reports · 2023Article
- Evaluation and Treatment of Acute Trauma Pain in Older Adults.Drugs & aging · 2023Article
- Age-Related Variations in Postoperative Pain Intensity across 10 Surgical Procedures: A Retrospective Study of Five Hospitals in South Korea.Journal of clinical medicine · 2023Article
- Article
- Analgesia Effect of Ultrasound-Guided Transversus Abdominis Plane Block Combined with Intravenous Analgesia After Cesarean Section: A Double-Blind Controlled Trial.Pain and therapy · 2022Article
- Postoperative pain management in non-traumatic emergency general surgery: WSES-GAIS-SIAARTI-AAST guidelines.World journal of emergency surgery : WJES · 2022Review
- New Insights Into the Pharmacological Management of Postoperative Pain: A Narrative Review.Cureus · 2022Review
- Glucose-insulin-potassium alleviates uterine cramping pain following cesarean delivery: A randomized, controlled trial.Frontiers in surgery · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this retrospective study, data of 2,435 patients who received fentanyl and ropivacaine-based patient-controlled epidural analgesia (PCEA) for pain relief after elective surgery under general or spinal anesthesia were reviewed. Differences in postoperative pain, incidence of patient-controlled analgesia (PCA)-related adverse effects, and risk factors for the need for rescue analgesics for 48 hours postsurgery in young (age 20-39 years) and elderly (age ≥70 years) patients were evaluated. Although there were no significant differences in postoperative pain intensity between the two groups until 6 hours postsurgery, younger patients experienced greater postoperative pain intensity compared with older patients 6-48 hours postsurgery. While younger patients exhibited greater incidence of numbness, motor weakness, and discontinuation of PCA postsurgery, elderly patients exhibited greater incidence of hypotension, nausea/vomiting, rescue analgesia, and antiemetic administration. Upon multivariate analysis, low fentanyl dosage and history of smoking were found to be associated with an increased need for rescue analgesia among younger patients, while physical status classification III/IV and thoracic surgery were associated with a decreased need for rescue analgesia among the elderly. Discontinuation of PCA was more frequent among younger patients than the elderly (18.5% vs 13.5%,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.