ArticleScientific reports2017
Discriminative and Distinct Phenotyping by Constrained Tensor Factorization.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- A Systematic Review of Topic Modeling Techniques for Electronic Health Records.Healthcare (Basel, Switzerland) · 2026Review
- Age-associated proteins explain the role of medial temporal lobe networks in Alzheimer's disease.GeroScience · 2025Article
- Unraveling Complex Temporal Patterns in EHRs via Robust Irregular Tensor Factorization.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2025Article
- MULTIPAR: Supervised Irregular Tensor Factorization with Multi-task Learning for Computational Phenotyping.Proceedings of machine learning research · 2023Article
- LogPar: Logistic PARAFAC2 Factorization for Temporal Binary Data with Missing Values.KDD : proceedings. International Conference on Knowledge Discovery & Data Mining · 2020Article
- Temporal phenotyping for transitional disease progress: An application to epilepsy and Alzheimer's disease.Journal of biomedical informatics · 2020Article
- Multimodal Phenotyping of Alzheimer's Disease with Longitudinal Magnetic Resonance Imaging and Cognitive Function Data.Scientific reports · 2020Article
- Article
- Privacy-Preserving Tensor Factorization for Collaborative Health Data Analysis.Proceedings of the ... ACM International Conference on Information & Knowledge Management. ACM International Conference on Information and Knowledge Management · 2019Article
- Distributed Tensor Decomposition for Large Scale Health Analytics.Proceedings of the ... International World-Wide Web Conference. International WWW Conference · 2019Article
- CP Tensor Decomposition with Cannot-Link Intermode Constraints.Proceedings of the ... SIAM International Conference on Data Mining. SIAM International Conference on Data Mining · 2019Article
- Discriminative Sleep Patterns of Alzheimer's Disease via Tensor Factorization.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2019Article
- GIFT: Guided and Interpretable Factorization for Tensors with an application to large-scale multi-platform cancer analysis.Bioinformatics (Oxford, England) · 2018Article
- The therapy is making me sick: how online portal communications between breast cancer patients and physicians indicate medication discontinuation.Journal of the American Medical Informatics Association : JAMIA · 2018Article
- Phenotyping of Korean patients with better-than-expected efficacy of moderate-intensity statins using tensor factorization.PloS one · 2018Article
- Phenotyping through Semi-Supervised Tensor Factorization (PSST).AMIA ... Annual Symposium proceedings. AMIA Symposium · 2018Article
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Authors and funding
5 authors.
Funding
Abstract
Adoption of Electronic Health Record (EHR) systems has led to collection of massive healthcare data, which creates oppor- tunities and challenges to study them. Computational phenotyping offers a promising way to convert the sparse and complex data into meaningful concepts that are interpretable to healthcare givers to make use of them. We propose a novel su- pervised nonnegative tensor factorization methodology that derives discriminative and distinct phenotypes. We represented co-occurrence of diagnoses and prescriptions in EHRs as a third-order tensor, and decomposed it using the CP algorithm. We evaluated discriminative power of our models with an Intensive Care Unit database (MIMIC-III) and demonstrated superior performance than state-of-the-art ICU mortality calculators (e.g., APACHE II, SAPS II). Example of the resulted phenotypes are sepsis with acute kidney injury, cardiac surgery, anemia, respiratory failure, heart failure, cardiac arrest, metastatic cancer (requiring ICU), end-stage dementia (requiring ICU and transitioned to comfort-care), intraabdominal conditions, and alcohol abuse/withdrawal.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.