ArticleScientific reports2017
A Puccinia striiformis f. sp. tritici secreted protein activates plant immunity at the cell surface.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 45 citations in OpenAlex.
- Genomics Research on the Road of Studying Biology and Virulence of Cereal Rust Fungi.Molecular plant pathology · 2025Review
- APlants (Basel, Switzerland) · 2025Article
- EffectorFrontiers in microbiology · 2025Article
- A Putative Effector Pst-18220, fromBiomolecules · 2024Article
- Variability and functional characterization of the Phakopsora pachyrhizi Egh16-like effectors.Genetics and molecular biology · 2024Article
- The nuclear effector MoHTR3 of Magnaporthe oryzae modulates host defence signalling in the biotrophic stage of rice infection.Molecular plant pathology · 2023Article
- The Biological Roles ofBiomolecules · 2023Review
- Ab Initio Modelling of the Structure of ToxA-like and MAX Fungal Effector Proteins.International journal of molecular sciences · 2023Article
- Engineering plant immune circuit: walking to the bright future with a novel toolbox.Plant biotechnology journal · 2023Review
- Prediction of effector protein structures from fungal phytopathogens enables evolutionary analyses.Nature microbiology · 2023Article
- Current Status and Future Perspectives of Genomics Research in the Rust Fungi.International journal of molecular sciences · 2022Review
- Identification of Secreted Protein Gene-Based SNP Markers Associated with Virulence Phenotypes ofInternational journal of molecular sciences · 2022Article
- The Small Secreted Protein FoSsp1 Elicits Plant Defenses and Negatively Regulates Pathogenesis inFrontiers in plant science · 2022Article
- Identification of Key Residues Essential for the Activation of Plant Immunity by Subtilisin FromFrontiers in microbiology · 2022Article
- Review
- At least three families of hyphosphere small secreted cysteine-rich proteins can optimize surface properties to a moderately hydrophilic state suitable for fungal attachment.Environmental microbiology · 2021Article
- Simple and efficient heterologous expression of necrosis-inducing effectors using the model plantPlant direct · 2021Article
- A Novel, Small Cysteine-Rich Effector, RsSCR10 inFrontiers in microbiology · 2021Article
- In-depth secretome analysis of Puccinia striiformis f. sp. tritici in infected wheat uncovers effector functions.Bioscience reports · 2020Article
- Whole-genome sequencing of Puccinia striiformis f. sp. tritici mutant isolates identifies avirulence gene candidates.BMC genomics · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pathogens secrete effector proteins to suppress host immunity, mediate nutrient uptake and subsequently enable parasitism. However, on non-adapted hosts, effectors can be detected as non-self by host immune receptors and activate non-host immunity. Nevertheless, the molecular mechanisms of effector triggered non-host resistance remain unknown. Here, we report that a small cysteine-rich protein PstSCR1 from the wheat rust pathogen Puccinia striiformis f. sp. tritici (Pst) activates immunity in the non-host solanaceous model plant Nicotiana benthamiana. PstSCR1 homologs were found to be conserved in Pst, and in its closest relatives, Puccinia graminis f. sp. tritici and Puccinia triticina. When PstSCR1 was expressed in N. benthamiana with its signal peptide, it provoked the plant immune system, whereas no stimulation was observed when it was expressed without its signal peptide. PstSCR1 expression in N. benthamiana significantly reduced infection capacity of the oomycete pathogens. Moreover, apoplast-targeted PstSCR1 triggered plant cell death in a dose dependent manner. However, in Brassinosteroid insensitive 1-Associated Kinase 1 (SERK3/BAK1) silenced N. benthamiana, cell death was remarkably decreased. Finally, purified PstSCR1 protein activated defence related gene expression in N. benthamiana. Our results show that a Pst-secreted protein, PstSCR1 can activate surface mediated immunity in non-adapted hosts and contribute to non-host resistance.
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