Evidence map›Paper›PMID 28442603›Full record

ArticlemBio2017

Arsa Thammahong, Alayna K Caffrey-Card, Sourabh Dhingra, Joshua J Obar, Robert A Cramer

Open access · goldAbstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. ZfpA-regulated chitin synthesis inAntimicrobial agents and chemotherapy · 2026
    Article
  3. Article
  4. Review
  5. Functional and molecular characterization ofJournal of medical microbiology · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Structures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogenProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  12. Role of theJournal of fungi (Basel, Switzerland) · 2024
    Article
  13. Article
  14. Chitin Biosynthesis inJournal of fungi (Basel, Switzerland) · 2023
    Review
  15. RNA-Seq Based Transcriptome Analysis ofJournal of fungi (Basel, Switzerland) · 2022
    Article
  16. Molecular investigations onRSC advances · 2022
    Article
  17. Review
  18. Article
  19. Osmolyte Signatures for the Protection ofJournal of fungi (Basel, Switzerland) · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Arsa ThammahongDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Alayna K Caffrey-CardDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Sourabh DhingraDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Joshua J ObarDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Robert A CramerDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA Robert.A.Cramer.JR@dartmouth.edu.
Dartmouth College · US

Funding

Vermont INBRE Administrative Supplement 2024 AWD 118P20GM103449 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI CHRISTOPHER S FRANCKLYN · 2012 to 2026
$58.4M
TRANSLATIONAL RESEARCH COREP30GM106394 · NIGMS · DARTMOUTH COLLEGE · PI MADDEN, DEAN R · 2013 to 2017
$6.1M
Hypoxia Adaptation and Fungal Virulence of Aspergillus fumigatusR01AI081838 · NIAID · MONTANA STATE UNIVERSITY - BOZEMAN · PI CRAMER, ROBERT ANDREW · 2009 to 2017
$2.9M
NIAID NIH HHS R01 AI081838NIGMS NIH HHS P20 GM103449NIGMS NIH HHS P30 GM106394
6 · The paper itself

Abstract

Trehalose biosynthesis is found in fungi but not humans. Proteins involved in trehalose biosynthesis are essential for fungal pathogen virulence in humans and plants through multiple mechanisms. Loss of canonical trehalose biosynthesis genes in the human pathogen

Indexed as

HomeostasisAnimalsAspergillus fumigatusCell WallChitin SynthaseChromatography, LiquidDisease Models, AnimalFungal ProteinsGene DeletionImmunoprecipitationInvasive Pulmonary AspergillosisMiceProtein Interaction MappingTandem Mass SpectrometryTrehaloseVirulenceChitin SynthaseFungal ProteinsTrehaloseAspergillus fumigatuscell wallchitinfilamentous fungipathogenesistrehalose

Identifiers

PMID28442603
PMCPMC5405227
OpenAlexW2609949910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.