ArticleDevelopmental cognitive neuroscience2017
Diurnal cortisol after early institutional care-Age matters.
Article in Developmental cognitive neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 31 citations in OpenAlex.
- Heightened sensitivity to the caregiving environment during adolescence: implications for recovery following early-life adversity.Journal of child psychology and psychiatry, and allied disciplines · 2021Trial
- Enhancing diurnal cortisol regulation among young children adopted internationally: A randomized controlled trial of a parenting-based intervention.Development and psychopathology · 2020Trial
- The adrenal is doing what it's supposed to do, you just don't understand it.Neurobiology of stress · 2026Article
- Conflict resolution dynamics with stable caregivers confer resilience for youth exposed to early caregiving-related adversity.Development and psychopathology · 2025Article
- Article
- Life stress influences the relationship between sex hormone fluctuation and affective symptoms in peripubertal female adolescents.Development and psychopathology · 2024Article
- Capitalizing on Neuroplasticity Across Development to Redirect Pathways from Juvenile Justice Involvement.Current topics in behavioral neurosciences · 2022Review
- Migration-related trauma and mental health among migrant children emigrating from Mexico and Central America to the United States: Effects on developmental neurobiology and implications for policy.Developmental psychobiology · 2021Review
- Pubertal transition with current life stress and support alters longitudinal diurnal cortisol patterns in adolescents exposed to early life adversity.Developmental psychobiology · 2021Article
- The persistent associations between early institutional care and diurnal cortisol outcomes among children adopted internationally.Developmental psychobiology · 2021Article
- Early Adversity and the Neotenous Human Brain.Biological psychiatry · 2020Review
- Working memory moderates the association between early institutional care and separation anxiety symptoms in late childhood and adolescence.Development and psychopathology · 2019Article
- Toward an animal model of borderline personality disorder.Psychopharmacology · 2019Review
- Development holds the key to understanding the interplay of nature versus nurture in shaping the individual.Developmental cognitive neuroscience · 2017Article
Corrections and comments
- Erratum issuedErratum.2020
Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
Several studies have shown that young children who have experienced early caregiving adversity (e.g. previously institutionalization (PI)) exhibit flattened diurnal cortisol slopes; however, less is known about how these patterns might differ between children and adolescents, since the transition between childhood and adolescence is a time of purported plasticity in the hypothalamic-pituitary-adrenal (HPA) axis. PI youth experience a massive improvement in caregiving environment once adopted into families; therefore we anticipated that a developmental increase in HPA axis plasticity during adolescence might additionally allow for an enhanced enrichment effect by the adoptive family. In a cross-sectional sample of 197 youths (PI and Comparison; 4-15 years old) we observed age-related group differences in diurnal slope. First replicating previous findings, PI children exhibited flattened diurnal slope. This group difference, however, was not observed in adolescents. Moderation analyses showed that pubertal development, increased time with family, and early adoption contributed to the steeper diurnal cortisol slope in PI adolescents. These findings add support to existing theories positing that the transition between middle childhood and adolescence may mark an additional sensitive period for diurnal cortisol patterning, allowing PI youth to benefit from the enriched environment provided by adoptive parents during this period of development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.