Evidence map›Paper›PMID 28441767›Full record

ArticleMolecules (Basel, Switzerland)2017

Inhibitory Effect of Triterpenoids from Panax ginseng on Coagulation Factor X.

Lingxin Xiong, Zeng Qi, Bingzhen Zheng, Zhuo Li, Fang Wang, Jinping Liu, Pingya Li

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Horticulture research · 2024
    Review
  5. Nutrients · 2024
    Review
  6. Review
  7. Journal of ginseng research · 2022
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lingxin XiongSchool of Pharmaceutical Sciences, Jilin University, Fujin Road 1266, Changchun 130021, China. xionglx14@mails.jlu.edu.cn.
Zeng QiSchool of Pharmaceutical Sciences, Jilin University, Fujin Road 1266, Changchun 130021, China. qizeng95@163.com.
Bingzhen ZhengSchool of Pharmaceutical Sciences, Jilin University, Fujin Road 1266, Changchun 130021, China. zhengbz15@mails.jlu.edu.cn.
Zhuo LiSchool of Pharmaceutical Sciences, Jilin University, Fujin Road 1266, Changchun 130021, China. rockefeller1988@sina.com.
Fang WangDepartment of Pathogen Biology, Basic Medical College, Jilin University, Changchun 130021, China. wf@jlu.edu.cn.
Jinping LiuSchool of Pharmaceutical Sciences, Jilin University, Fujin Road 1266, Changchun 130021, China. liujp@jlu.edu.cn.
Pingya LiSchool of Pharmaceutical Sciences, Jilin University, Fujin Road 1266, Changchun 130021, China. lipy@jlu.edu.cn.
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enzymes involved in the coagulation process have received great attention as potential targets for the development of oral anti-coagulants. Among these enzymes, coagulation factor Xa (FXa) has remained the center of attention in the last decade. In this study, 16 ginsenosides and two sapogenins were isolated, identified and quantified. To determine the inhibitory potential on FXa, the chromogenic substrates method was used. The assay suggested that compounds

Indexed as

Binding SitesChromatography, High Pressure LiquidDrug Evaluation, PreclinicalFactor XFactor Xa InhibitorsGinsenosidesKineticsMolecular Docking SimulationPanaxPartial Thromboplastin TimePlant ExtractsProtein BindingProteolysisThrombinFactor XFactor Xa InhibitorsGinsenosidesPlant ExtractsThrombincoagulation factor Xaginsenginhibitorsmolecular dockingthrombintriterpenoids

Identifiers

PMID28441767
PMCPMC6154706
OpenAlexW2610023049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.