Evidence map›Paper›PMID 28441084›Full record

ReviewAutophagy2017

The emergence of noncoding RNAs as Heracles in autophagy.

Jian Zhang, Peiyuan Wang, Lin Wan, Shouping Xu, Da Pang

Open access · bronzeAbstract readReview
In one paragraph

Review in Autophagy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 2 syntheses or guidelines pooled it, 102 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Advances in the study of autophagy in breast cancer.Breast cancer (Tokyo, Japan) · 2024
    Review
  10. H19: An Oncogenic Long Non-coding RNA in Colorectal Cancer.The Yale journal of biology and medicine · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Noncoding RNAs in Drug Resistance of Gastrointestinal Stromal Tumor.Frontiers in cell and developmental biology · 2022
    Review
  16. Review
  17. Roles and mechanisms of CircRNAs in ovarian cancer.Frontiers in cell and developmental biology · 2022
    Review
  18. Review
  19. Review
  20. Review

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jian Zhanga Department of Breast Surgery , Harbin Medical University Cancer Hospital , Harbin , China.
Peiyuan Wanga Department of Breast Surgery , Harbin Medical University Cancer Hospital , Harbin , China.
Lin Wana Department of Breast Surgery , Harbin Medical University Cancer Hospital , Harbin , China.
Shouping Xua Department of Breast Surgery , Harbin Medical University Cancer Hospital , Harbin , China.
Da Panga Department of Breast Surgery , Harbin Medical University Cancer Hospital , Harbin , China.
Third Affiliated Hospital of Harbin Medical University · CNHarbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macroautophagy/autophagy is a catabolic process that is widely found in nature. Over the past few decades, mounting evidence has indicated that noncoding RNAs, ranging from small noncoding RNAs to long noncoding RNAs (lncRNAs) and even circular RNAs (circRNAs), mediate the transcriptional and post-transcriptional regulation of autophagy-related genes by participating in autophagy regulatory networks. The differential expression of noncoding RNAs affects autophagy levels at different physiological and pathological stages, including embryonic proliferation and differentiation, cellular senescence, and even diseases such as cancer. We summarize the current knowledge regarding noncoding RNA dysregulation in autophagy and investigate the molecular regulatory mechanisms underlying noncoding RNA involvement in autophagy regulatory networks. Then, we integrate public resources to predict autophagy-related noncoding RNAs across species and discuss strategies for and the challenges of identifying autophagy-related noncoding RNAs. This article will deepen our understanding of the relationship between noncoding RNAs and autophagy, and provide new insights to specifically target noncoding RNAs in autophagy-associated therapeutic strategies.

Indexed as

AnimalsAutophagyHumansMicroRNAsModels, BiologicalPhagosomesRNARNA, CircularRNA, UntranslatedMicroRNAsRNARNA, CircularRNA, UntranslatedautophagybioinformaticscircRNAslong noncoding RNAsmicroRNAs

Identifiers

PMID28441084
PMCPMC5486373
OpenAlexW2609131214

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.