ReviewAnnual review of genomics and human genetics2017
Precisely Where Are We Going? Charting the New Terrain of Precision Prevention.
Review in Annual review of genomics and human genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Review
- The rise of diversity terminology in biomedical research.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Mapping the state-of-the-art of the barriers for personalized preventive approaches worldwide: A scoping review of reviews.PloS one · 2025Article
- Ethics of early detection of disease risk factors: A scoping review.BMC medical ethics · 2024Article
- A precision environmental health approach to prevention of human disease.Nature communications · 2023Review
- DNA-Methylation Signatures of Tobacco Smoking in a High Cardiovascular Risk Population: Modulation by the Mediterranean Diet.International journal of environmental research and public health · 2023Article
- The New Precision Stewards?Journal of personalized medicine · 2022Article
- Recommendations on the use and reporting of race, ethnicity, and ancestry in genetic research: Experiences from the NHLBI TOPMed program.Cell genomics · 2022Article
- Transparency, trust, and community welfare: towards a precision public health ethics framework for the genomics era.Genome medicine · 2020Article
- Health Equity and Implementation Science in Heart, Lung, Blood, and Sleep-Related Research: Emerging Themes From the 2018 Saunders-Watkins Leadership Workshop.Circulation. Cardiovascular quality and outcomes · 2019Article
- Genomic Essentialism: Its Provenance and Trajectory as an Anticipatory Ethical Concern.The Hastings Center report · 2019Article
- On the utilization of polygenic risk scores for therapeutic targeting.PLoS genetics · 2019Review
- Precision Strategies as a Timely and Unifying Framework for Ongoing Prevention Science Advances.Prevention science : the official journal of the Society for Prevention Research · 2019Article
- Can Precision Medicine Reduce the Burden of Diabetes?Ethnicity & disease · 2019Article
- Adolescent and Parental Attitudes About Return of Genomic Research Results: Focus Group Findings Regarding Decisional Preferences.Journal of empirical research on human research ethics : JERHRE · 2018Article
- Genomic medicine for kidney disease.Nature reviews. Nephrology · 2018Review
- Nature vs. Nurture in Precision Education: Insights of Parents and the Public.AJOB empirical bioethicsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
In addition to genetic data, precision medicine research gathers information about three factors that modulate gene expression: lifestyles, environments, and communities. The relevant research tools-epidemiology, environmental assessment, and socioeconomic analysis-are those of public health sciences rather than molecular biology. Because these methods are designed to support inferences and interventions addressing population health, the aspirations of this research are expanding from individualized treatment toward precision prevention in public health. The purpose of this review is to explore the emerging goals and challenges of such a shift to help ensure that the genomics community and public policy makers understand the ethical issues at stake in embracing and pursuing precision prevention. Two emerging goals bear special attention in this regard: (a) public health risk reduction strategies, such as screening, and (b) the application of genomic variation studies to understand and reduce health disparities among population groups.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.